Optogenetic inactivation of the entopeduncular nucleus improves forelimb akinesia in a Parkinson's disease model
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112551
Abstract: We performed optogenetic inactivation of rats' entopeduncular nucleus (EP, homologous to primates' globus pallidus interna (GPi)) and investigated the therapeutic effect in a rat model of PD. 6-Hydroxydopamine (6-OHDA)-induced hemiparkinsonian rats were injected with either… read more here.
Keywords: entopeduncular nucleus; optogenetic inactivation; illumination; model ... See more keywords
Contribution of the Entopeduncular Nucleus and the Globus Pallidus to the Control of Locomotion and Visually Guided Gait Modifications in the Cat.
Sign Up to like & getrecommendations! Published in 2020 at "Cerebral cortex"
DOI: 10.1093/cercor/bhaa106
Abstract: We tested the hypothesis that the entopeduncular (EP) nucleus (feline equivalent of the primate GPi) and the globus pallidus (GPe) contribute to both the planning and execution of locomotion and voluntary gait modifications in the… read more here.
Keywords: entopeduncular nucleus; globus pallidus; gait modifications; locomotion ... See more keywords
The effect of 5‐HT1A receptor agonists on the entopeduncular nucleus is modified in 6‐hydroxydopamine‐lesioned rats
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15437
Abstract: l‐DOPA prolonged treatment leads to disabling motor complications as dyskinesia that could be decreased by drugs acting on 5‐HT1A receptors. Since the internal segment of the globus pallidus, homologous to the entopeduncular nucleus in rodents,… read more here.
Keywords: entopeduncular nucleus; ht1a receptor; lesioned rats; hydroxydopamine ... See more keywords
New Subregions of the Mouse Entopeduncular Nucleus Defined by the Complementary Immunoreactivities for Substance P and Cannabinoid Type-1 Receptor Combined with Distributions of Different Neuronal Types
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0208-22.2022
Abstract: Abstract The entopeduncular nucleus (EPN) and substantia nigra pars reticulata (SNr) constitute the output nuclei of the basal ganglia, but studies on the EPN are limited compared with those on the SNr. Both nuclei receive… read more here.
Keywords: epn; substance cannabinoid; entopeduncular nucleus; nucleus ... See more keywords