Orai1 is an Entotic Ca2+ Channel for Non‐Apoptotic Cell Death, Entosis in Cancer Development
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DOI: 10.1002/advs.202205913
Abstract: Entosis is a non‐apoptotic cell death process that forms characteristic cell‐in‐cell structures in cancers, killing invading cells. Intracellular Ca2+ dynamics are essential for cellular processes, including actomyosin contractility, migration, and autophagy. However, the significance of… read more here.
Keywords: cell death; non apoptotic; apoptotic cell; entosis ... See more keywords
Identification of the entosis-related prognostic signature and tumour microenvironment in hepatocellular carcinoma on the basis of bioinformatics analysis and experimental validation
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-025-01580-8
Abstract: Liver cancer ranks among the deadliest cancers worldwide. Entosis, a recently uncovered method of cell death, has not yet been fully explored for its relevance to HCC. A bioinformatics analysis was performed to determine the… read more here.
Keywords: entosis related; bioinformatics analysis; entosis; risk ... See more keywords
Abstract 103: Syndecan-1 Is a key mediator of entosis and cellular competition in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-103
Abstract: Entosis, a form of cell-in-cell (CIC) structure formation where one cell invades and becomes internalized by another, has long been observed in various malignancies and is considered a critical cellular process in cancer progression, with… read more here.
Keywords: cancer; entosis; cell; mediator ... See more keywords
Entosis: From Cell Biology to Clinical Cancer Pathology
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DOI: 10.3390/cancers12092481
Abstract: Simple Summary We review published clinico-histopathological studies establishing entosis an important prognostic and predictor factor in various cancer types. We also propose a new model to study this phenomenon, which involves active entry of one… read more here.
Keywords: carcinoma; pathology; biology; entosis ... See more keywords
Mitosis can drive cell cannibalism through entosis
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DOI: 10.7554/elife.27134
Abstract: Entosis is a form of epithelial cell cannibalism that is prevalent in human cancer, typically triggered by loss of matrix adhesion. Here, we report an alternative mechanism for entosis in human epithelial cells, driven by… read more here.
Keywords: mitosis drive; cell cannibalism; cell; entosis ... See more keywords