Orai1 is an Entotic Ca2+ Channel for Non‐Apoptotic Cell Death, Entosis in Cancer Development
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205913
Abstract: Entosis is a non‐apoptotic cell death process that forms characteristic cell‐in‐cell structures in cancers, killing invading cells. Intracellular Ca2+ dynamics are essential for cellular processes, including actomyosin contractility, migration, and autophagy. However, the significance of… read more here.
Keywords: cell death; non apoptotic; apoptotic cell; entosis ... See more keywords
Entosis: From Cell Biology to Clinical Cancer Pathology
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DOI: 10.3390/cancers12092481
Abstract: Simple Summary We review published clinico-histopathological studies establishing entosis an important prognostic and predictor factor in various cancer types. We also propose a new model to study this phenomenon, which involves active entry of one… read more here.
Keywords: carcinoma; pathology; biology; entosis ... See more keywords
Mitosis can drive cell cannibalism through entosis
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DOI: 10.7554/elife.27134
Abstract: Entosis is a form of epithelial cell cannibalism that is prevalent in human cancer, typically triggered by loss of matrix adhesion. Here, we report an alternative mechanism for entosis in human epithelial cells, driven by… read more here.
Keywords: mitosis drive; cell cannibalism; cell; entosis ... See more keywords