Indirect calculation of monoclonal antibodies in nanoparticles using the radiolabeling process with technetium 99 metastable as primary factor: Alternative methodology for the entrapment efficiency
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.02.017
Abstract: Graphical abstract Figure. No Caption available. HighlightsNovel methodology for the development of magnetic core mesoporous silica.Radiolabeling process of monoclonal antibodies with 99mTc.Efficient methodology to calculate the Incorporation of monoclonal antibodies into nanoparticles by radiolabeling process.… read more here.
Keywords: methodology; entrapment efficiency; monoclonal antibodies; mesoporous silica ... See more keywords
Molecular insight into silk fibroin based delivery vehicle for amphiphilic drugs: Synthesis, characterization and molecular dynamics studies
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DOI: 10.1016/j.molliq.2019.112156
Abstract: Abstract Recent emergence of natural biopolymers as drug delivery vehicles is attributed to their biodegradability and less systemic toxicity. Here, we have synthesized curcumin, indomethacin and emodin-loaded silk fibroin nanoparticles (SFNs) and characterized several pharmacokinetic… read more here.
Keywords: entrapment efficiency; molecular dynamics; delivery; silk ... See more keywords
Influence of probe-sonication process on drug entrapment efficiency of liposomes loaded with a hydrophobic drug
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DOI: 10.1080/00914037.2018.1434651
Abstract: ABSTRACT Since probe-sonication is commonly used to homogenize liposomal formulations, it is necessary to investigate its influence on drug entrapment efficiency (EE) of liposomes. In this study, ibuprofen-loaded liposomes (IBU-Lip) dispersion was prepared from ibuprofen… read more here.
Keywords: entrapment efficiency; drug entrapment; sonication; drug ... See more keywords
Experimental study and mathematical modeling for encapsulation of fentanyl citrate drug in nanostructured lipid carrier
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DOI: 10.1080/07391102.2019.1599732
Abstract: Abstract The aim of this study is to prepare a nanostructured lipid carrier (NLC) containing Fentanyl Citrate drug. The materials were selected in a way to achieve a nanostructure with lower particle size and higher… read more here.
Keywords: entrapment efficiency; drug entrapment; drug; size ... See more keywords
Design of temozolomide-loaded proliposomes and lipid crystal nanoparticles with industrial feasible approaches: comparative assessment of drug loading, entrapment efficiency, and stability at plasma pH
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DOI: 10.1080/08982104.2020.1748648
Abstract: Abstract Temozolomide is a drug approved for treating glioblastomas, which has 100% oral bioavailability but gets degraded at physiological pH thus having very short half-life and only 20–30% brain bioavailability. Due to its amphiphilic nature,… read more here.
Keywords: drug loading; entrapment efficiency; lipid crystal; crystal nanoparticles ... See more keywords
QbD Based Development, Characterization and Pharmacokinetic Evaluation of Enzalutamide-Loaded Cyclodextrin Nano Sponges for Enhanced Drug Delivery
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DOI: 10.5530/ijper.20255427
Abstract: Aim/Background: The aim of this study was to enhance the bioavailability of Enzalutamide by developing cross-linked cyclodextrin nanosponges loaded with the drug (EZL-CDNS). The objective of the work is to thoroughly investigate the impact of… read more here.
Keywords: release; entrapment efficiency; drug; ezl cdns ... See more keywords