A new entry to highly functionalized pyrroles via a cascade reaction of α-amino esters and alkynals.
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DOI: 10.1039/d0cc02964e
Abstract: Here, we developed an expedient access route to highly functionalized pyrroles from readily available α-amino acid ester hydrochlorides and alkynals via a cascade condensation/intramolecular cyclization followed by a unique C-N ester migration process. A variety… read more here.
Keywords: amino; via cascade; functionalized pyrroles; entry highly ... See more keywords