Sertraline Is an Effective SARS-CoV-2 Entry Inhibitor Targeting the Spike Protein
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DOI: 10.1128/jvi.01245-22
Abstract: The study shows SRT is an effective entry inhibitor against infection of SARS-CoV-2, which is currently prevalent globally. SRT targets the S protein of SARS-CoV-2 and is effective against a panel of SARS-CoV-2 variants. ABSTRACT… read more here.
Keywords: infection sars; srt; infection; sars cov ... See more keywords
A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor
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DOI: 10.3390/v11090874
Abstract: CXC chemokine receptor 4 (CXCR4) is a co-receptor for HIV-1 entry into target cells. Its natural ligand, the chemokine SDF-1, inhibits viral entry mediated by this receptor. However, the broad expression pattern of CXCR4 and… read more here.
Keywords: hiv entry; hiv; entry inhibitor; sdf ... See more keywords