Three-Dimensional Visualization of Viral Structure, Entry, and Replication Underlying the Spread of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Reviews"
DOI: 10.1021/acs.chemrev.1c01062
Abstract: The global spread of SARS-CoV-2 has proceeded at an unprecedented rate. Remarkably, characterization of the virus using modern tools in structural biology has also progressed at exceptional speed. Advances in electron-based imaging techniques, combined with… read more here.
Keywords: entry replication; spread sars; three dimensional; biology ... See more keywords
Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00304
Abstract: Influenza viruses cause approximately half a million deaths every year worldwide. Vaccines are available but partially effective, and the number of antiviral medications is limited. Thus, it is crucial to develop therapeutic strategies to counteract… read more here.
Keywords: aryl sulfonamide; entry replication; via hemagglutinin; influenza viruses ... See more keywords
Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01581
Abstract: Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait provides influenza with the advantage of access to the nuclear machinery during replication. However, it also increases the complexity of… read more here.
Keywords: virion assembly; entry replication; cell entry; entry ... See more keywords