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   Articles with "env specific" as a keyword



HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

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recommendations! Published in 2017 at "Journal of Virology"

DOI: 10.1128/jvi.00544-17

Abstract: ABSTRACT Immune control of human immunodeficiency virus type 1 (HIV) infection is typically associated with effective Gag-specific CD8+ T-cell responses. We here focus on HLA-B*14, which protects against HIV disease progression, but the immunodominant HLA-B*14-restricted… read more here.

Keywords: response; control; hiv; hla restricted ... See more keywords
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Production of HIV-1 Env-Specific Antibodies Mediating Innate Immune Functions Depends on Cognate Interleukin-21- Secreting CD4+ T Cells

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recommendations! Published in 2021 at "Journal of Virology"

DOI: 10.1128/jvi.02097-20

Abstract: To develop a vaccine or immunotherapy that would cure the HIV-1 infection, it is important to identify helper T cells able to mount an efficient antibody response. Here, we demonstrate that the generation of HIV-1… read more here.

Keywords: env specific; innate; hiv; specific antibodies ... See more keywords

Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection

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recommendations! Published in 2022 at "mSphere"

DOI: 10.1128/msphere.00839-21

Abstract: Women of childbearing age are three times more likely to contract HIV infection than their male counterparts. Poor HIV testing rates coupled with low adherence to antiretroviral therapy (ART) result in a high risk of… read more here.

Keywords: env specific; hiv; infection; infant rhesus ... See more keywords

Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0172524

Abstract: Our central hypothesis is that protection against HIV infection will be powerfully influenced by the magnitude and quality of the B cell response. Although sterilizing immunity, mediated by pre-formed abundant and potent antibodies is the… read more here.

Keywords: response; infection; antibody; dysregulation ... See more keywords

Quantifying Anti-HIV Envelope-Specific Antibodies in Plasma from HIV Infected Individuals

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recommendations! Published in 2019 at "Viruses"

DOI: 10.3390/v11060487

Abstract: Quantifying HIV Envelope (Env)-specific antibodies in HIV+ plasma is useful for interpreting antibody dependent cellular cytotoxicity assay results. HIV Env, the only viral protein expressed on the surface of infected cells, has a native trimeric… read more here.

Keywords: hiv; hiv envelope; gp120; env specific ... See more keywords