Protecting from Envelope Stress: Variations on the Phage-Shock-Protein Theme.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in microbiology"
DOI: 10.1016/j.tim.2016.10.001
Abstract: During envelope stress, critical inner-membrane functions are preserved by the phage-shock-protein (Psp) system, a stress response that emerged from work with Escherichia coli and other Gram-negative bacteria. Reciprocal regulatory interactions and multiple effector functions are… read more here.
Keywords: envelope stress; envelope; stress; shock protein ... See more keywords
Envelope stress responses defend against type six secretion system attacks independently of immunity proteins
Sign Up to like & getrecommendations! Published in 2020 at "Nature microbiology"
DOI: 10.1038/s41564-020-0672-6
Abstract: The arms race among microorganisms is a key driver in the evolution of not only the weapons but also defence mechanisms. Many Gram-negative bacteria use the type six secretion system (T6SS) to deliver toxic effectors… read more here.
Keywords: envelope stress; system; six secretion; type six ... See more keywords
The Wsp system of Pseudomonas aeruginosa links surface sensing and cell envelope stress
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117633119
Abstract: Significance Bacteria must respond quickly to environmental changes to survive. One way bacteria can respond to environmental stress is by undergoing a lifestyle transition from individual, free-swimming cells to a surface-associated community called a biofilm… read more here.
Keywords: stress; envelope stress; pseudomonas aeruginosa; wsp system ... See more keywords
Mutual interplay between ArcA and σE orchestrates envelope stress response in Shewanella oneidensis.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental microbiology"
DOI: 10.1111/1462-2920.15060
Abstract: To survive and thrive in harsh and ever-changing environments, intricate mechanisms have evolved for bacterial cells to monitor perturbations impacting the integrity of their envelope and to mount an appropriate response to contain or repair… read more here.
Keywords: envelope stress; response; shewanella oneidensis; interplay ... See more keywords
Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14178
Abstract: Molecular components of the Brucella abortus cell envelope play a major role in its ability to infect, colonize and survive inside mammalian host cells. In this study, we have defined a role for a conserved… read more here.
Keywords: envelope stress; brucella; eipa; stress resistance ... See more keywords
Defining the regulon of genes controlled by σE, a key regulator of the cell envelope stress response in Streptomyces coelicolor
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14250
Abstract: The extracytoplasmic function (ECF) σ factor, σE, is a key regulator of the cell envelope stress response in Streptomyces coelicolor. Although its role in maintaining cell wall integrity has been known for over a decade,… read more here.
Keywords: envelope stress; cell; cell envelope; stress response ... See more keywords
Regulation of Flagellum Biosynthesis in Response to Cell Envelope Stress in Salmonella enterica Serovar Typhimurium
Sign Up to like & getrecommendations! Published in 2018 at "mBio"
DOI: 10.1128/mbio.00736-17
Abstract: ABSTRACT Flagellum-driven motility of Salmonella enterica serovar Typhimurium facilitates host colonization. However, the large extracellular flagellum is also a prime target for the immune system. As consequence, expression of flagella is bistable within a population… read more here.
Keywords: envelope stress; biosynthesis; salmonella; cell envelope ... See more keywords
Distinct domains of Escherichia coli IgaA connect envelope stress sensing and down-regulation of the Rcs phosphorelay across subcellular compartments
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007398
Abstract: In enterobacteria, the Rcs system (Regulator of capsule synthesis) monitors envelope integrity and induces a stress response when damages occur in the outer membrane or in the peptidoglycan layer. Built around a two-component system, Rcs… read more here.
Keywords: envelope stress; igaa; distinct domains; rcs ... See more keywords
The Essential UPP Phosphatase Pair BcrC and UppP Connects Cell Wall Homeostasis during Growth and Sporulation with Cell Envelope Stress Response in Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02403
Abstract: The bacterial cell wall separates the cell from its surrounding and protects it from environmental stressors. Its integrity is maintained by a highly regulated process of cell wall biosynthesis. The membrane-located lipid II cycle provides… read more here.
Keywords: envelope stress; cell; cell envelope; cell wall ... See more keywords
Disbalancing Envelope Stress Responses as a Strategy for Sensitization of Escherichia coli to Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.653479
Abstract: Disbalancing envelope stress responses was investigated as a strategy for sensitization of Escherichia coli to antimicrobial agents. Seventeen isogenic strains were selected from the KEIO collection with deletions in genes corresponding to the σE, Cpx,… read more here.
Keywords: envelope stress; pspb mutant; sensitization;
The Cell Envelope Stress Response of Bacillus subtilis towards Laspartomycin C
Sign Up to like & getrecommendations! Published in 2020 at "Antibiotics"
DOI: 10.3390/antibiotics9110729
Abstract: Cell wall antibiotics are important tools in our fight against Gram-positive pathogens, but many strains become increasingly resistant against existing drugs. Laspartomycin C is a novel antibiotic that targets undecaprenyl phosphate (UP), a key intermediate… read more here.
Keywords: envelope stress; cell envelope; response; resistance ... See more keywords