Physiochemical properties of enveloped viruses and arginine dictate inactivation
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202000342
Abstract: Therapeutic protein manufacturing would benefit by having an arsenal of ways to inactivate viruses. There have been many publications on the virus inactivation ability of arginine at pH 4.0, but the mechanism of this inactivation… read more here.
Keywords: virus inactivation; enveloped viruses; properties enveloped; physiochemical properties ... See more keywords
Arginine‐enveloped virus inactivation and potential mechanisms
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Progress"
DOI: 10.1002/btpr.2931
Abstract: Arginine synergistically inactivates enveloped viruses at a pH or temperature that does little harm to proteins, making it a desired process for therapeutic protein manufacturing. However, the mechanisms and optimal conditions for inactivation are not… read more here.
Keywords: enveloped viruses; viral inactivation; arginine; inactivation ... See more keywords
Broad‐spectrum antiviral activity of Spatholobus suberectus Dunn against SARS‐CoV‐2, SARS‐CoV‐1, H5N1, and other enveloped viruses
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7452
Abstract: The current COVID‐19 pandemic caused by SARS‐Cov‐2 is responsible for more than 6 million deaths globally. The development of broad‐spectrum and cost‐effective antivirals is urgently needed. Medicinal plants are renowned as a complementary approach in… read more here.
Keywords: spatholobus suberectus; suberectus dunn; enveloped viruses; sars cov ... See more keywords
Glass Wool Concentration Optimization for the Detection of Enveloped and Non-enveloped Waterborne Viruses
Sign Up to like & getrecommendations! Published in 2019 at "Food and Environmental Virology"
DOI: 10.1007/s12560-019-09378-0
Abstract: An extremely affordable virus concentration method based on adsorption-elution to glass wool and subsequent reconcentration through polyethylene glycol 6000 (PEG) precipitation was optimized to recover not only non-enveloped viruses but also enveloped viruses. Hepatitis A… read more here.
Keywords: elution; glass wool; enveloped viruses; non enveloped ... See more keywords
Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.03.014
Abstract: Abstract Several compounds extracted from spices and herbs exhibit antiviral effects in vitro, suggesting potential pharmacological uses. Curcumin, a component of turmeric, has been used as a food additive and herbal supplement due to its… read more here.
Keywords: zika chikungunya; enveloped viruses; inhibits zika; virus ... See more keywords
Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation Vaccines
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.02.054
Abstract: Enveloped viruses enter cells by inducing fusion of viral and cellular membranes, a process catalyzed by a specialized membrane-fusion protein expressed on their surface. This review focuses on recent structural studies of viral fusion proteins… read more here.
Keywords: enveloped viruses; fusion; common features; next generation ... See more keywords
Cryo-electron tomography of enveloped viruses.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2021.08.005
Abstract: Viruses are macromolecular machineries that hijack cellular metabolism for replication. Enveloped viruses comprise a large variety of RNA and DNA viruses, many of which are notorious human or animal pathogens. Despite their importance, the presence… read more here.
Keywords: cryo electron; enveloped viruses; biology; electron tomography ... See more keywords
Antimicrobial Lipstick: Bio-Based Composition against Viruses, Bacteria, and Fungi.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19460
Abstract: The COVID-19 pandemic has speeded up the race to find materials that could help limit or avoid the spread of SARS-CoV-2, while infections by multidrug-resistant bacteria and fungi are now becoming a serious threat. In… read more here.
Keywords: viruses bacteria; bacteria fungi; antimicrobial lipstick; bio based ... See more keywords
Microbicidal actives with virucidal efficacy against SARS-CoV-2 and other beta- and alpha-coronaviruses and implications for future emerging coronaviruses and other enveloped viruses
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84842-1
Abstract: Mitigating the risk of acquiring coronaviruses including SARS-CoV-2 requires awareness of the survival of virus on high-touch environmental surfaces (HITES) and skin, and frequent use of targeted microbicides with demonstrated efficacy. The data on stability… read more here.
Keywords: virucidal efficacy; enveloped viruses; microbicidal actives; efficacy ... See more keywords
Three-dimensional insights into human enveloped viruses in vitro and in situ
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20210433
Abstract: Viruses can be enveloped or non-enveloped, and require a host cell to replicate and package their genomes into new virions to infect new cells. To accomplish this task, viruses hijack the host-cell machinery to facilitate… read more here.
Keywords: dimensional insights; cryo; insights human; three dimensional ... See more keywords
Enveloped viruses show increased propensity to cross-species transmission and zoonosis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2215600119
Abstract: The transmission of viruses between different host species is a major source of emerging diseases and is of particular concern in the case of zoonotic transmission from mammals to humans. Several zoonosis risk factors have… read more here.
Keywords: zoonosis; viruses show; cross species; propensity ... See more keywords