The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22522
Abstract: Exposure to environmental chemicals is now well recognized as a significant factor contributing to the global burden of disease; however, there remain critical gaps in understanding the types of biological mechanisms that link environmental chemicals… read more here.
Keywords: impact environmental; database driven; contaminants extracellular; extracellular vesicles ... See more keywords
Cell-Based Bioassay to Screen Environmental Chemicals and Human Serum for Total Glucocorticogenic Activity.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4903
Abstract: Glucocorticoids (GCs) are steroid hormones that have systemic effects that are mediated by the glucocorticoid receptor (GR). Environmental chemicals that disrupt GR signaling and/or GC homeostasis could adversely affect the health of human and non-human… read more here.
Keywords: chemicals human; glucocorticogenic activity; human serum; cell based ... See more keywords
Emerging roles of long non‐coding RNAs in the toxicology of environmental chemicals
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3595
Abstract: Environmental chemicals (ECs) are drawing great attention to their effects on health and their toxicological mechanisms are being investigated. Long non‐coding RNA (lncRNA) is a class of RNA with more than 200 nucleotides and does… read more here.
Keywords: emerging roles; long non; non coding; expression ... See more keywords
Effects of environmental chemicals on the proliferation and differentiation of neural stem cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22829
Abstract: The objective of the present study was to explore the effects of environmental chemicals, such as methyl mercury, paraquat, and bisphenol A, on cell proliferation and apoptosis, as well as the expression levels of neuronal… read more here.
Keywords: effects environmental; proliferation; differentiation; environmental chemicals ... See more keywords
Exposure to environmental chemicals and perinatal psychopathology.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114835
Abstract: Women are nearly twice as likely to develop mood disorders compared with men, and incidence is greatest during reproductive transitions, including pregnancy and postpartum. Because these periods are characterized by dramatic hormonal and physiologic changes,… read more here.
Keywords: chemicals perinatal; perinatal psychopathology; environmental chemicals; exposure environmental ... See more keywords
Extravillous Trophoblast Migration and Invasion: Impact of Environmental Chemicals and Pharmaceuticals.
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2021.11.008
Abstract: During pregnancy, the migration and invasion of extravillous trophoblasts (EVTs) into the maternal uterus is essential for proper development of the placenta and fetus. During the first trimester, EVTs engraft and remodel maternal spiral arteries… read more here.
Keywords: invasion; evt migration; migration; chemicals pharmaceuticals ... See more keywords
Environmental chemicals and metabolic disruption in primary and secondary human parathyroid tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Surgery"
DOI: 10.1016/j.surg.2020.06.010
Abstract: BACKGROUND The incidence of primary hyperparathyroidism has increased 300% in the United States in the past 30 years, and secondary hyperparathyroidism is almost universal in patients with end-stage renal disease. We assessed the presence of… read more here.
Keywords: biphenyl polychlorinated; human parathyroid; polychlorinated biphenyl; environmental chemicals ... See more keywords
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114876
Abstract: The present study adapted an existing high content imaging-based high-throughput phenotypic profiling (HTPP) assay known as "Cell Painting" for bioactivity screening of environmental chemicals. This assay uses a combination of fluorescent probes to label a… read more here.
Keywords: based high; bioactivity; phenotypic; environmental chemicals ... See more keywords
Advances in neural organoid systems and their application in neurotoxicity testing of environmental chemicals
Sign Up to like & getrecommendations! Published in 2021 at "Genes and Environment"
DOI: 10.1186/s41021-021-00214-1
Abstract: Due to the complex structure and function of central nervous system (CNS), human CNS in vitro modeling is still a great challenge. Neurotoxicity testing of environmental chemicals mainly depends on the traditional animal models, which… read more here.
Keywords: testing environmental; environmental chemicals; neural organoid; organoid systems ... See more keywords
Infant Dietary Exposures to Environmental Chemicals and Infant/Child Health: A Critical Assessment of the Literature
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Health Perspectives"
DOI: 10.1289/ehp1954
Abstract: Background: The benefits of breastfeeding to the infant and mother have been well documented. It is also well known that breast milk contains environmental chemicals, and numerous epidemiological studies have explored relationships between background levels… read more here.
Keywords: literature; infant dietary; dietary exposures; environmental chemicals ... See more keywords
Baby Steps Forward: Recommendations for Better Understanding Environmental Chemicals in Breast Milk and Infant Formula
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Health Perspectives"
DOI: 10.1289/ehp4804
Abstract: The infant diet is typically limited to breast milk and/or infant formula for the first months of life. Yet relatively little is known about the environmental chemicals present in these foods and their potential shortand… read more here.
Keywords: milk; milk infant; breast milk; environmental chemicals ... See more keywords