Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Toxicology"
DOI: 10.1007/s00204-018-2252-6
Abstract: Adductomics is expected to be useful in the characterization of the exposome, which is a new paradigm for studying the sum of environmental causes of diseases. DNA adductomics is emerging as a powerful method for… read more here.
Keywords: vitro vivo; dna; environmental exposures; approach ... See more keywords
Before the beginning: environmental exposures and reproductive and obstetrical outcomes.
Sign Up to like & getrecommendations! Published in 2019 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2019.08.001
Abstract: There is growing consensus that preconception exposure to environmental toxins can adversely affect fertility, pregnancy, and fetal development, which may persist into the neonatal and adult periods and potentially have multigenerational effects. Here we review… read more here.
Keywords: exposures reproductive; preconception; beginning environmental; environmental exposures ... See more keywords
Environmental Exposures in Reproductive Health.
Sign Up to like & getrecommendations! Published in 2019 at "Obstetrics and gynecology clinics of North America"
DOI: 10.1016/j.ogc.2019.04.005
Abstract: Our genetic makeup and environment interact. Evidence has emerged demonstrating preconception and prenatal exposure to toxic agents have a profound effect on reproductive health. We cannot change our genetics, but we can change our environment.… read more here.
Keywords: health; environmental exposures; reproductive health; exposures reproductive ... See more keywords
A comprehensive assessment of environmental exposures and the medical history guides multidisciplinary discussion in interstitial lung disease.
Sign Up to like & getrecommendations! Published in 2021 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2021.106333
Abstract: BACKGROUND Multidisciplinary discussion (MDD) is widely recommended for patients with interstitial lung disease (ILD), but published primary data from MDD has been scarce, and factors influencing MDD other than chest computed tomography (CT) and lung… read more here.
Keywords: mdd; environmental exposures; histopathology; history ... See more keywords
OCCUPATIONAL ENVIRONMENTAL EXPOSURES AND CARDIAC STRUCTURE AND FUNCTION: THE ECHOCARDIOGRAPHIC STUDY OF LATINOS (ECHO-SOL)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)32207-1
Abstract: The pathways by which environmental exposures contribute to the pathogenesis of cardiovascular disease are not well described. Our objective was to determine the association of toxic occupational exposures with cardiac structure and function as measured… read more here.
Keywords: cardiac structure; environmental exposures; exposures cardiac; structure function ... See more keywords
Paper-in-Facemask Device for Direct Mass Spectrometry Analysis of Human Respiratory Aerosols and Environmental Exposures via Wearable Continuous-Flow Adsorptive Sampling: A Proof-of-Concept Study.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03406
Abstract: Facemasks are considered safe and wearable devices that cover the human mouth and nose for filtering exhaled aerosols and inhaled environmental exposures; various chemical and environmental residues thus can remain in facemasks. Therefore, direct analysis… read more here.
Keywords: mass spectrometry; analysis; environmental exposures; paper ... See more keywords
Toxicoepigenetics and Environmental Health: Challenges and Opportunities.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00445
Abstract: The rapidly growing field of toxicoepigenetics seeks to understand how toxicant exposures interact with the epigenome to influence disease risk. Toxicoepigenetics is a promising field of environmental health research, as integrating epigenetics into the field… read more here.
Keywords: toxicology; health; environmental exposures; disease ... See more keywords
Environmental exposures as a risk factor for fibrolamellar carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Modern Pathology"
DOI: 10.1038/modpathol.2017.7
Abstract: Fibrolamellar carcinoma was first described in 1956. Subsequent large studies failed to identify cases before 1939 (the start of the World War II). This finding, combined with the presence of aryl hydrocarbon receptors on the… read more here.
Keywords: exposures risk; carcinoma; world war; environmental exposures ... See more keywords
106 Establishing a Physiologically Relevant in Vitro Airway Model to Assess the Impacts of Environmental Exposures, Like Smoking, on Covid-19 Susceptibility.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Work Exposures and Health"
DOI: 10.1093/annweh/wxac087.207
Abstract: Air-liquid interface (ALI) cultures are commonly used for 3D modelling of the human airways and to examine the effects of direct exposure to airborne toxicants. We explored the suitability of human epithelial cell lines (RPMI… read more here.
Keywords: environmental exposures; susceptibility; model; 106 establishing ... See more keywords
GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbx025
Abstract: Genome-wide association study (GWAS)-based pathway association analysis is a powerful approach for the genetic studies of human complex diseases. However, the genetic confounding effects of environment exposure-related genes can decrease the accuracy of GWAS-based pathway… read more here.
Keywords: analysis; environmental exposures; genetic confounding; gwas summary ... See more keywords
The role of environmental exposures and gene–environment interactions in the etiology of systemic lupus erythematous
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13448
Abstract: Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease, whose etiology includes both genetic and environmental factors. Individual genetic risk factors likely only account for about one‐third of observed heritability among individuals with a… read more here.
Keywords: environmental exposures; environment interactions; etiology; risk ... See more keywords