Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates
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DOI: 10.1016/j.ejmech.2018.01.086
Abstract: Abstract Several hitherto unknown (E)-but-2-enyl nucleoside phosphonoamidate analogs (ANPs) were prepared directed with nitrogen reagents by cross-metathesis in water-under ultrasound irradiation. Two diastereoisomers were formally identified by X-ray diffraction. These compounds were evaluated against a… read more here.
Keywords: enyl; antiviral activity; enyl nucleoside; highly convergent ... See more keywords