Predicting Cytotoxicity and Enzymatic Activity of Diverse Chemicals Using Goldfish Scale Tissue and Topminnow Hepatoma Cell Line‐based Data
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Informatics"
DOI: 10.1002/minf.201800127
Abstract: Quantitative structure‐toxicity relationship (QSTR) models were built for two in vitro endpoints: cytotoxicity and enzymatic activity of diverse chemicals to goldfish (Crassius auratus) scale tissue (GFS) and topminnow (Poeciliopsis lucida) hepatoma cell line (PLHC‐1), respectively. The… read more here.
Keywords: qstr models; diverse chemicals; cytotoxicity; enzymatic activity ... See more keywords
Unveiling the enzymatic activity of a dimeric LDH isoform and its implications for allosteric inhibition strategies
Sign Up to like & getrecommendations! Published in 2025 at "Protein Science"
DOI: 10.1002/pro.70367
Abstract: Lactate dehydrogenase (LDH) is a key enzyme in cancer metabolism, with isoforms LDH5 and LDH1 supporting glycolysis and oxidative lactate metabolism, respectively. While the development of competitive LDH inhibitors has faced diverse challenges, allosteric strategies… read more here.
Keywords: ldh; tetramerization; unveiling enzymatic; activity ... See more keywords
Enzymatic Activity of Candida spp. from Oral Cavity and Urine in Children with Nephrotic Syndrome.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2017_46
Abstract: Oral colonization with Candida spp. is not synonymous with a systemic active infection. The aim of the study was to evaluate enzymatic activity of Candida strains isolated from the oral cavity in patients with nephrotic… read more here.
Keywords: oral cavity; candida; candida spp; enzymatic activity ... See more keywords
Essential role of a conserved aspartate for the enzymatic activity of plasmanylethanolamine desaturase
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-022-04238-w
Abstract: Plasmalogens are an abundant class of glycerophospholipids in the mammalian body, with special occurrence in the brain and in immune cell membranes. Plasmanylethanolamine desaturase (PEDS1) is the final enzyme of plasmalogen biosynthesis, which introduces the… read more here.
Keywords: peds1; enzymatic activity; essential role; plasmanylethanolamine desaturase ... See more keywords
Controlling enzymatic activity by immobilization on graphene oxide
Sign Up to like & getrecommendations! Published in 2017 at "Die Naturwissenschaften"
DOI: 10.1007/s00114-017-1459-3
Abstract: In this study, graphene oxide (GO) has been applied as a matrix for enzyme immobilization. The protein adsorption capacity of GO is much higher than of other large surface area carbonaceous materials. Its structure and… read more here.
Keywords: graphene oxide; enzymatic activity; activity immobilization; controlling enzymatic ... See more keywords
Effects of proanthocyanidin-functionalized hydroxyapatite nanoparticles on dentin bonding
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-024-05836-7
Abstract: To evaluate the effect of proanthocyanidin-functionalized hydroxyapatite nanoparticles (nHAp_PA) used as pretreatment at different concentrations on the microtensile bond strength (µTBS) and endogenous enzymatic activity (MMPs) on pH-cycled dentin after 24 h and 6 months… read more here.
Keywords: control; proanthocyanidin functionalized; functionalized hydroxyapatite; hydroxyapatite nanoparticles ... See more keywords
Preparation and enzymatic activity of Fe3O4-IDA-Ni/NAD kinase magnetic catalyst
Sign Up to like & getrecommendations! Published in 2020 at "Korean Journal of Chemical Engineering"
DOI: 10.1007/s11814-019-0472-y
Abstract: The use of oxidoreductases as biocatalysts for industrial production of valuable compounds has a strong demand for NADP. Herein, we prepared superparamagnetic NAD kinase catalyst to synthesize NADP in vitro. First, Fe3O4 particles were synthesized… read more here.
Keywords: enzymatic activity; kinase; fe3o4; nad kinase ... See more keywords
Effect of circadian rhythm, photoperiod, and molt cycle on digestive enzymatic activity of Macrobrachium tenellum juveniles
Sign Up to like & getrecommendations! Published in 2017 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2017.05.029
Abstract: Abstract The objective of this research was to determine the circadian cycle of basal digestive enzymatic activity of the freshwater prawn Macrobrachium tenellum and the effect exerted by the photoperiod and molting cycle on digestive… read more here.
Keywords: enzymatic activity; photoperiod; digestive enzymatic; cycle digestive ... See more keywords
Structural and biochemical characterization of FabK from Thermotoga maritima.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.11.141
Abstract: TM0800 from Thermotoga maritima is one of the hypothetical proteins with unknown function. The crystal structure determined at 2.3 Å resolution reveals a two domain structure: the N-terminal domain forming a barrel and the C-terminal forming… read more here.
Keywords: enzymatic activity; thermotoga; thermotoga maritima; fabk ... See more keywords
Adsorption of urease as part of a complex protein mixture onto soil and its implications for enzymatic activity
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2021.108026
Abstract: Abstract Understanding adsorption of important proteins as part of a complex protein mixture onto surfaces such as soil is critical for numerous environmental applications. In this study, we investigated the adsorption of urease as part… read more here.
Keywords: enzymatic activity; soil; activity; adsorption ... See more keywords
Insights into the effects of single and combined divalent copper and humic acid on the performance, microbial community and enzymatic activity of activated sludge from sequencing batch reactor.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126165
Abstract: The performance, microbial community and enzymatic activity of activated sludge from four identical sequencing batch reactors (SBRs) were compared by treating synthetic wastewater under the single and combined divalent copper (Cu2+) at 20 mg/L and humic… read more here.
Keywords: enzymatic activity; activity activated; cu2; activated sludge ... See more keywords