Enzymatic Defluorination of a Terminally Monofluorinated Pentyl Moiety: Oxidative or Hydrolytic Mechanism?
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DOI: 10.1124/dmd.123.001501
Abstract: Fluorination of organic compounds plays an important role in the chemical and pharmaceutical industry and is often applied to improve physicochemical parameters or modify pharmacological properties. Although oxidative and reductive defluorination have been shown to… read more here.
Keywords: defluorination; terminally monofluorinated; mechanism; defluorination terminally ... See more keywords