Identification of the effect of N-glycan modification and its sialylation on proteolytic stability and glucose-stabilizing activity of glucagon-like peptide 1 by site-directed enzymatic glycosylation
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DOI: 10.1039/d2ra05872c
Abstract: In this study, an approach to prepare long-acting glucagon-like peptide 1 (GLP-1) by site-directed enzymatic glycosylation with homogeneous biantennary complex-type N-glycan has been developed. All the N-glycan-modified GLP-1 analogues preserved an unchanged secondary structure. The… read more here.
Keywords: directed enzymatic; site directed; glucose stabilizing; enzymatic glycosylation ... See more keywords
Enzymatic glycosylation of oleanane-type triterpenoids
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DOI: 10.1080/10286020.2018.1478818
Abstract: Abstract Glycosylation is an effective approach to improve the druggability of natural products by increasing their water solubility. In this work, we report the glycosylation of oleanane-type triterpenoids by a recombinant microbial glycosyltransferase YjiC1. A… read more here.
Keywords: oleanane type; glycosylation; type triterpenoids; enzymatic glycosylation ... See more keywords
Effect of enzymatic glycosylation on the structure and properties of wheat gluten protein fibers
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DOI: 10.1177/15589250211000337
Abstract: Wheat gluten proteins are good raw materials for preparing fibers due to their excellent viscoelasticity. However, protein fibers made directly from wheat gluten have poor mechanical properties. In... read more here.
Keywords: structure properties; wheat gluten; glycosylation structure; effect enzymatic ... See more keywords
Advances and Challenges in Enzymatic C-glycosylation of Flavonoids in Plants.
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DOI: 10.2174/1381612828666220422085128
Abstract: Flavonoid glycosides play required determinant roles in plants and have considerable potential for applications in medicine and biotechnology. Glycosyltransferases transfer a sugar moiety from uridine diphosphate-activated sugar molecules to an acceptor flavonoid via C-O and… read more here.
Keywords: glycosylation flavonoids; enzymatic glycosylation; flavonoids plants; advances challenges ... See more keywords