Advanced Strategies of Enzyme Activity Regulation for Biomedical Applications
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200358
Abstract: Enzymes are important macromolecular biocatalysts that accelerate chemical and biochemical reactions in living organisms. Most human diseases are related to alterations in enzyme activity. Moreover, enzymes are potential therapeutic tools for treating different diseases, such… read more here.
Keywords: biomedical applications; enzyme activity; activity; advanced strategies ... See more keywords
Within‐species trade‐offs in plant‐stimulated soil enzyme activity and growth, flowering, and seed size
Sign Up to like & getrecommendations! Published in 2018 at "Ecology and Evolution"
DOI: 10.1002/ece3.4623
Abstract: Abstract Soil microbial communities affect species demographic rates of plants. In turn, plants influence the composition and function of the soil microbiome, potentially resulting in beneficial feedbacks that alter their fitness and establishment. For example,… read more here.
Keywords: soil; seed; plant; enzyme activity ... See more keywords
The effect of astaxanthin and cadmium on rat erythrocyte G6PD, 6PGD, GR, and TrxR enzymes activities in vivo and on rat erythrocyte 6PGD enzyme activity in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22170
Abstract: In this study, the effects of astaxanthin (AST) that belongs to carotenoid family and cadmium (Cd), which is an important heavy metal, on rat erythrocyte G6PD, 6PGD, GR, and TrxR enzyme activities in vivo and… read more here.
Keywords: enzyme activity; 6pgd enzyme; rat erythrocyte; enzyme ... See more keywords
Recovery of enzyme activity in biotinidase deficient individuals during early childhood.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inherited metabolic disease"
DOI: 10.1002/jimd.12490
Abstract: Deficiency of the biotinidase (BTD) enzyme is an inborn error of biotin metabolism caused by bi-allelic pathogenic variants in the BTD gene. There are two forms, partial and profound BTD deficiency, which both can be… read more here.
Keywords: recovery; deficiency; enzyme activity; btd ... See more keywords
Characterization of exonic variants of uncertain significance in very long‐chain acyl‐CoA dehydrogenase identified through newborn screening
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12492
Abstract: Very long‐chain acyl‐CoA dehydrogenase deficiency (VLCADD) is an autosomal recessive disease resulting from mutations in the ACADVL gene and is among the disorders tested for in newborn screening (NBS). Confirmatory sequencing following suspected VLCADD NBS… read more here.
Keywords: acadvl; vlcad; enzyme activity; activity ... See more keywords
Novel mRNA therapy restores GALT protein and enzyme activity in a zebrafish model of classic galactosemia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12512
Abstract: Messenger RNA (mRNA) has emerged as a novel therapeutic approach for inborn errors of metabolism. Classic galactosemia (CG) is an inborn error of galactose metabolism caused by a severe deficiency of galactose‐1‐phosphate:uridylyltransferase (GALT) activity leading… read more here.
Keywords: enzyme activity; zebrafish model; activity; activity zebrafish ... See more keywords
Ultrasound for pectinase modification: an investigation into potential mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10472
Abstract: BACKGROUND Today, ultrasound is increasingly utilized in enzyme modification. Strongly dependent on the specific operational conditions, the modification effect brought by ultrasound can be activation and inactivation of enzymes. This work aims to study the… read more here.
Keywords: enzyme activity; free radical; effect; ultrasound intensity ... See more keywords
Effect of metabolosome encapsulation peptides on enzyme activity, coaggregation, incorporation, and bacterial microcompartment formation
Sign Up to like & getrecommendations! Published in 2020 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1010
Abstract: Metabolosomes, catabolic bacterial microcompartments (BMCs), are proteinaceous organelles that are associated with the breakdown of metabolites such as propanediol and ethanolamine. They are composed of an outer multicomponent protein shell that encases a specific metabolic… read more here.
Keywords: protein; enzyme activity; formation; effect ... See more keywords
Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9236-2_22
Abstract: Spectrophotometric analysis of metabolic enzyme activity from homogenized tissues is a valuable method for investigating mitochondrial content and capacity. Enzyme activity is normally measured in single cuvette spectrophotometers, requiring a large sample volume and low… read more here.
Keywords: assays spectrophotometric; enzyme activity; spectrophotometric measurement; microplate assays ... See more keywords
Characterization of ecto-nucleotidases in human oviducts with an improved approach simultaneously identifying protein expression and in situ enzyme activity
Sign Up to like & getrecommendations! Published in 2017 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-017-1627-8
Abstract: Extracellular ATP and its hydrolysis product adenosine modulate various reproductive functions such as those taking place in oviducts, including contraction, beating of cilia, and maintenance of fluid composition that, in turn, influences sperm capacitation and… read more here.
Keywords: enzyme activity; nucleotidases human; human oviducts; ecto ... See more keywords
Cellular antioxidant enzyme activity and biomarkers for oxidative stress are affected by heat stress
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Biometeorology"
DOI: 10.1007/s00484-019-01769-z
Abstract: Heat stress (HS) causes oxidative stress and cellular changes in an attempt to detoxify the harmful effects of reactive oxygen species (ROS). However, how ROS affect different organs in chickens under acute and chronic HS… read more here.
Keywords: enzyme activity; heat stress; stress; heat ... See more keywords