Polyphosphate Chain Length Determination in the Range of Two to Several Hundred P-Subunits with a New Enzyme Assay and 31P NMR.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00567
Abstract: Currently, 31P NMR is the only analytical method that quantitatively determines the average chain length of long inorganic polyphosphate (>80 P-subunits). In this study, an enzyme assay is presented that determines the average chain length… read more here.
Keywords: 31p nmr; chain; chain length; polyphosphate ... See more keywords
Improving the laboratory diagnosis of pyruvate kinase deficiency
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DOI: 10.1111/bjh.17483
Abstract: Pyruvate kinase (PK) deficiency is an autosomal recessive disease caused by mutations in the PKLR gene, which reduce erythrocyte PK enzyme activity and result in decreased energy synthesis in red cells, causing haemolytic anaemia. Historically,… read more here.
Keywords: kinase deficiency; pyruvate kinase; enzyme assay;
Coumarin-Based Sulfonamide Derivatives as Potential DPP-IV Inhibitors: Pre-ADME Analysis, Toxicity Profile, Computational Analysis, and In Vitro Enzyme Assay
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DOI: 10.3390/molecules28031004
Abstract: Recent research on dipeptidyl peptidase-IV (DPP-IV) inhibitors has made it feasible to treat type 2 diabetes mellitus (T2DM) with minimal side effects. Therefore, in the present investigation, we aimed to discover and develop some coumarin-based… read more here.
Keywords: dpp; vitro enzyme; coumarin based; enzyme assay ... See more keywords