DNA Damage by an essential enzyme: A delicate balance act on the tightrope.
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DOI: 10.1016/j.dnarep.2019.102639
Abstract: DNA topoisomerases are essential for DNA metabolic processes such as replication and transcription. Since DNA is double stranded, the unwinding needed for these processes results in DNA supercoiling and catenation of replicated molecules. Changing the… read more here.
Keywords: dna damage; dna; essential enzyme; enzyme delicate ... See more keywords