Fluorescent carbon dot‐gated multifunctional mesoporous silica nanocarriers for redox/enzyme dual‐responsive targeted and controlled drug delivery and real‐time bioimaging
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.03.019
Abstract: Graphical abstract Figure. No caption available. ABSTRACT A distinctive and personalized nanocarrier is described here for controlled and targeted antitumor drug delivery and real‐time bioimaging by combining a redox/enzyme dual‐responsive disulfide‐conjugated carbon dot with mesoporous… read more here.
Keywords: dual responsive; redox enzyme; delivery; drug ... See more keywords
Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc06376e
Abstract: Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide dendrimer cores, trigger selective inhibition of lysosomal β-glucocerebrosidase or α-mannosidase depending on valency and topology, offering new opportunities in multitargeted drug… read more here.
Keywords: multivalent glycoligands; dual specificity; lectin enzyme; glycoligands lectin ... See more keywords
pH/enzyme dual sensitive and nucleus-targeting dendrimer nanoparticles to enhance the antitumour activity of doxorubicin
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2055569
Abstract: Abstract Direct delivery of drugs into the nucleus is a promising nanotechnology therapy, since the nucleus is one of the most important organelles controlling cell proliferation and apoptosis. Here, we report a nucleus-targeting nanocarrier for… read more here.
Keywords: dual sensitive; peg; pamam; nucleus targeting ... See more keywords