Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018
Sign Up to like & getrecommendations! Published in 2018 at "Chromatographia"
DOI: 10.1007/s10337-018-3663-5
Abstract: The necessity to develop automated methods for the fast screening of new libraries of compounds and the identification of active entities from natural mixtures has led to an increasing interest in the development of immobilized… read more here.
Keywords: immobilized enzyme; reactors overview; drug; enzyme reactors ... See more keywords
Fabrication of immobilized enzyme reactors with pillar arrays into polydimethylsiloxane microchip.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.02.048
Abstract: This paper demonstrates the design, efficiency and applicability of a simple and inexpensive microfluidic immobilized enzymatic reactor (IMER) for rapid protein digestion. The high surface-to-volume ratio (S/V) of the reactor was achieved by forming pillars… read more here.
Keywords: pillar arrays; immobilized enzyme; digestion; fabrication immobilized ... See more keywords
Advantages of Hydrogel-Based 3D-Printed Enzyme Reactors and Their Limitations for Biocatalysis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2018.00211
Abstract: The development of process steps catalyzed by immobilized enzymes usually encompasses the screening of enzyme variants, as well as the optimization of immobilization protocols and process parameters. Direct immobilization of biocatalysts by physical entrapment into… read more here.
Keywords: immobilization; hydrogel based; advantages hydrogel; based printed ... See more keywords