Preliminary Investigation of Microbiome and Dietary Differences in Patients with Phenylketonuria on Enzyme Substitution Therapy Compared to Traditional Therapies.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Academy of Nutrition and Dietetics"
DOI: 10.1016/j.jand.2021.12.011
Abstract: BACKGROUND Phenylketonuria (PKU) is an inborn error of metabolism that impairs the function of the enzyme phenylalanine hydroxylase (PAH). Historical treatment includes limiting dietary phenylalanine (Phe) consumption while supplementing with medical food; however, this treatment… read more here.
Keywords: analysis; substitution therapy; microbiome; liberalized diet ... See more keywords
Phenylalanine ammonia lyase (PAL): From discovery to enzyme substitution therapy for phenylketonuria.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular genetics and metabolism"
DOI: 10.1016/j.ymgme.2018.06.002
Abstract: Phenylketonuria (PKU) is a genetic inborn error in metabolism that impacts many people globally, with profound individual and societal consequences when left untreated. The journey of phenylalanine ammonia lyase (PAL) from plant enzyme to enzyme… read more here.
Keywords: enzyme substitution; lyase pal; enzyme; phenylalanine ammonia ... See more keywords