Computational protein design repurposed to explore enzyme vitality and help predict antibiotic resistance
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DOI: 10.3389/fmolb.2022.905588
Abstract: In response to antibiotics that inhibit a bacterial enzyme, resistance mutations inevitably arise. Predicting them ahead of time would aid target selection and drug design. The simplest resistance mechanism would be to reduce antibiotic binding… read more here.
Keywords: protein design; enzyme vitality; vitality; computational protein ... See more keywords