Emerging Role of Deubiquitinating Enzymes (DUBs) in Melanoma Pathogenesis
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DOI: 10.3390/cancers14143371
Abstract: Simple Summary Metastatic melanoma is one of the most aggressive skin tumors with a poor prognosis. Despite the efficacy of immunotherapy and targeted therapies, advanced melanoma patients are often refractory to treatments and have high… read more here.
Keywords: melanoma; enzymes dubs; role deubiquitinating; emerging role ... See more keywords
Targeting Deubiquitinating Enzymes (DUBs) That Regulate Mitophagy via Direct or Indirect Interaction with Parkin
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012105
Abstract: The quality control of mitochondria is critical for the survival of cells, and defects in the pathways required for this quality control can lead to severe disease. A key quality control mechanism in cells is… read more here.
Keywords: targeting deubiquitinating; quality control; enzymes dubs; regulate mitophagy ... See more keywords