Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism
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DOI: 10.1093/nar/gkac072
Abstract: Abstract Ribosome assembly is an essential process that is linked to human congenital diseases and tumorigenesis. While great progress has been made in deciphering mechanisms governing ribosome biogenesis in eukaryotes, an inventory of factors that… read more here.
Keywords: 60s subunit; polyamine metabolism; wide rnai; enzymes polyamine ... See more keywords