Articles with "eo3001" as a keyword



Abstract B142: EO3001: A novel agent for ARID1A mutant cancers

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Published in 2025 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-25-b142

Abstract: ARID1A mutations are among the most common genetic alterations in cancer, occurring in approximately 65% of ovarian clear cell carcinoma (OCCC) and up to 10% of all solid tumors. These mutations disrupt chromatin remodeling and… read more here.

Keywords: arid1a mutant; cancer; agent; eo3001 ... See more keywords

Abstract 4298: Investigating the potential of EO3001 as a therapeutic agent for clear cell ovarian cancers harboring ARID1A mutations

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-4298

Abstract: Clear cell ovarian cancer (CCOC) is a histological subtype of ovarian cancer that is resistant to standard chemotherapies. Although it accounts for only around 6% of all ovarian cancer cases, it is the second leading… read more here.

Keywords: cancer; cell ovarian; cell; ccoc ... See more keywords