Presynaptic dopaminergic function in early-onset Alzheimer's disease: an FP-CIT image study
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2019.10.007
Abstract: We aimed to investigate whether amyloid-β (Aβ) positive early-onset Alzheimer's disease (EOAD) patients have presynaptic dopaminergic deficits on in vivo 18F-FP-CIT PET imaging. We enrolled 34 EOAD patients and 9 cognitively normal controls (NC), all of… read more here.
Keywords: presynaptic dopaminergic; early onset; cit; disease ... See more keywords
Dissecting the clinical heterogeneity of early-onset Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Psychiatry"
DOI: 10.1038/s41380-022-01531-9
Abstract: Early-onset Alzheimer’s disease (EOAD) is a rare but particularly devastating form of AD. Though notable for its high degree of clinical heterogeneity, EOAD is defined by the same neuropathological hallmarks underlying the more common, late-onset… read more here.
Keywords: onset alzheimer; early onset; eoad; alzheimer disease ... See more keywords
Characterizing Early-Onset Alzheimer Disease Using Multiprobe PET/MRI
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000004663
Abstract: Purpose Early-onset Alzheimer disease (EOAD) is rare, highly heterogeneous, and associated with poor prognosis. This AT(N) Framework–based study aimed to compare multiprobe PET/MRI findings between EOAD and late-onset Alzheimer disease (LOAD) patients and explore potential… read more here.
Keywords: pet mri; disease; eoad; multiprobe pet ... See more keywords
The genes associated with early-onset Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.23738
Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the most cases of dementia, which is characterized by the deposition of dense plaques of amyloid beta (Aβ) plaques and neurofibrillary tangles consisting of… read more here.
Keywords: onset; early onset; alzheimer disease; disease ... See more keywords
A Comparison of Behavioral and Psychological Symptoms of Dementia (BPSD) and BPSD Sub-Syndromes in Early-Onset and Late-Onset Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-215061
Abstract: Background: Behavioral and psychological symptoms of dementia (BPSD) have a large impact on the quality of life of patients with Alzheimer’s disease (AD). Few studies have compared BPSD between early-onset (EOAD) and late-onset (LOAD) patients,… read more here.
Keywords: load; bpsd; eoad; alzheimer disease ... See more keywords
Dementia-related genetic variants in an Italian population of early-onset Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.969817
Abstract: Early-onset Alzheimer’s disease (EOAD) is the most common form of early-onset dementia. Although three major genes have been identified as causative, the genetic contribution to the disease remains unsolved in many patients. Recent studies have… read more here.
Keywords: onset alzheimer; disease; alzheimer disease; early onset ... See more keywords