Articles with "eoc" as a keyword



Experiences of Health Facility Childbirth in Sub-Saharan Africa: A Systematic Review of Qualitative Evidence

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Published in 2022 at "Maternal and Child Health Journal"

DOI: 10.1007/s10995-022-03383-9

Abstract: Access to skilled birth attendance has been prioritised as an intervention to minimise burden of maternal deaths in sub-Saharan Africa (SSA). However, poor experience of care (EoC) is impeding progress. We conducted a systematic review… read more here.

Keywords: review; sub saharan; health; systematic review ... See more keywords

Correlation between polymorphisms in IGF2/H19 gene locus and epithelial ovarian cancer risk in Chinese population.

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Published in 2020 at "Genomics"

DOI: 10.1016/j.ygeno.2020.02.002

Abstract: To investigate the association between SNPs in human IGF2/H19 gene locus and epithelial ovarian cancer (EOC) risk, we performed a case-control study in 422 individuals (219 EOC patients and 203 cancer-free controls). Four SNPs (rs2525885,… read more here.

Keywords: risk; gene locus; eoc; igf2 h19 ... See more keywords

Novel treatment options in platinum-sensitive recurrent ovarian cancer: A review.

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Published in 2019 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2018.10.023

Abstract: Epithelial ovarian cancer (EOC) is the leading cause of death due to gynecologic malignancy. The majority of advanced stage EOC patients, even those who respond well to frontline therapy, will ultimately recur and succumb to… read more here.

Keywords: eoc; treatment; review; platinum sensitive ... See more keywords

Integrated proteomics and scRNA-seq analyses of ovarian cancer reveal molecular subtype-associated cell landscapes and immunotherapy targets

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Published in 2024 at "British Journal of Cancer"

DOI: 10.1038/s41416-024-02894-2

Abstract: Epithelial ovarian cancer (EOC) represents the most lethal gynaecological malignancy, yet understanding the connections between its molecular subtypes and their therapeutic implications remains incomplete. We conducted mass spectrometry-based proteomics analyses of 154 EOC tumour samples… read more here.

Keywords: cancer; scrna seq; ovarian cancer; cell ... See more keywords

Identification of novel biomarkers for epithelial ovarian cancer through machine learning and explainable artificial intelligence using in silico and in vitro analysis

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-25901-9

Abstract: Epithelial ovarian cancer (EOC) is a lethal gynecological malignancy. Ongoing research aimed to identify novel biomarkers and develop combined algorithms to improve diagnosis and prognosis prediction for EOC. RNA-seq related to EOC were obtained from… read more here.

Keywords: epithelial ovarian; machine learning; ovarian cancer; novel biomarkers ... See more keywords

Platinum-induced upregulation of ITGA6 promotes chemoresistance and spreading in ovarian cancer

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Published in 2024 at "EMBO Molecular Medicine"

DOI: 10.1038/s44321-024-00069-3

Abstract: Platinum (PT)-resistant Epithelial Ovarian Cancer (EOC) grows as a metastatic disease, disseminating in the abdomen and pelvis. Very few options are available for PT-resistant EOC patients, and little is known about how the acquisition of… read more here.

Keywords: itga6; dissemination; vivo; adhesion ... See more keywords

Overexpression of long noncoding RNA HOXB-AS3 indicates an unfavorable prognosis and promotes tumorigenesis in epithelial ovarian cancer via Wnt/β-catenin signaling pathway

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Published in 2019 at "Bioscience Reports"

DOI: 10.1042/bsr20190906

Abstract: Long noncoding RNA HOXB cluster antisense RNA 3 (HOXB-AS3) has been reported to be dysregulated in several tumors. The present study mainly aims at the investigation in how HOXB-AS3 works in epithelial ovarian cancer (EOC)… read more here.

Keywords: wnt catenin; hoxb; catenin signaling; hoxb as3 ... See more keywords

circDENND4C, a novel serum marker for epithelial ovarian cancer, acts as a tumor suppressor by downregulating miR-200b/c.

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Published in 2023 at "Annals of medicine"

DOI: 10.1080/07853890.2023.2185289

Abstract: RESEARCH OBJECTIVE To explore the diagnostic value of circ-DENN domain containing 4 C (circDENND4C) in epithelial ovarian cancer (EOC) and the corresponding mechanism. METHODS We determined the expression of circDENND4C and miR-200b/c in tissues and serum… read more here.

Keywords: serum; mir 200b; expression; serum circdennd4c ... See more keywords
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The impact of body composition on treatment in ovarian cancer: a current insight

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Published in 2021 at "Expert Review of Clinical Pharmacology"

DOI: 10.1080/17512433.2021.1937125

Abstract: ABSTRACT Introduction Epithelial ovarian cancer (EOC) remains the most lethal of gynecological cancers. Sarcopenia and low Skeletal Muscle Radiodensity (SMD) are highly prevalent in EOC. Cross sectional imaging via MRI and CT are considered the… read more here.

Keywords: eoc; body composition; ovarian cancer;

Ovarian Cancer Therapy.

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Published in 2025 at "Cold Spring Harbor perspectives in medicine"

DOI: 10.1101/cshperspect.a038232

Abstract: Significant advances in basic and translational research have improved our understanding of the molecular alterations and biological vulnerabilities of the different histologic subsets of epithelial ovarian cancer (EOC). This has led to clinical trials that… read more here.

Keywords: oncology; cancer; treatment; ovarian cancer ... See more keywords

EP844 Elaidic acid promotes cell proliferation and migration via LSR in epithelial ovarian cancer

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Published in 2019 at "International Journal of Gynecological Cancer"

DOI: 10.1136/ijgc-2019-esgo.893

Abstract: Introduction/Background Previously, we identified lipolysis-stimulated lipoprotein receptor (LSR) as a poor prognostic factor of epithelial ovarian cancer (EOC), and we demonstrated anti-cancer effect of our newly developed anti-LSR monoclonal antibody (mAb) against LSR-positive EOC in… read more here.

Keywords: cell proliferation; via lsr; lsr; lsr positive ... See more keywords