Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer
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DOI: 10.1097/cad.0000000000001339
Abstract: Cisplatin (DDP) resistance limits therapeutic efficacy in patients diagnosed with ovarian cancer. Purvalanol A (Pur) is a novel cyclin-dependent kinase (CDK) inhibitor that has been demonstrated to induce apoptosis in various cancer cells. The present… read more here.
Keywords: ovarian cancer; combination; eoc cells; resistance ... See more keywords
CircBNC2 affects epithelial ovarian cancer progression through the miR-223-3p/LARP4 axis
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DOI: 10.1097/cad.0000000000001423
Abstract: Epithelial ovarian cancer (EOC) is one of the most serious cancer. Circular RNA BNC2 (circBNC2) expression was decreased in EOC tissues. However, the molecular mechanism of circBNC2 remains unknown. The expression of circBNC2, microRNA-223-3p (miR-223-3p),… read more here.
Keywords: circbnc2; mir 223; 223 larp4; eoc cells ... See more keywords
Sohlh2 alleviates malignancy of EOC cells under hypoxia via inhibiting the HIF1α/CA9 signaling pathway
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DOI: 10.1515/hsz-2019-0119
Abstract: Abstract Epithelial ovarian cancer (EOC) is the most common and deadly ovarian cancer. Most of the patients have abdominal/pelvic invasion and metastasis at the time of diagnosis, but the underlying mechanism remains unclear. Insufficiency of… read more here.
Keywords: ca9 signaling; signaling pathway; sohlh2 alleviates; eoc cells ... See more keywords
Metastatic Voyage of Ovarian Cancer Cells in Ascites with the Assistance of Various Cellular Components
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DOI: 10.3390/ijms23084383
Abstract: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and has a unique metastatic route using ascites, known as the transcoelomic root. However, studies on ascites and contained cellular components have not yet been… read more here.
Keywords: cellular components; cancer cells; ovarian cancer; eoc cells ... See more keywords