Mendelian randomization suggests a potential causal effect of eosinophil count on influenza vaccination responsiveness
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28394
Abstract: Currently, the clinical factors affecting immune responses to influenza vaccines have not been systematically explored. The mechanism of low responsiveness to influenza vaccination (LRIV) is complicated and not thoroughly elucidated. Thus, we integrate our in‐house… read more here.
Keywords: eosinophil; eosinophil count; influenza vaccination; mendelian randomization ... See more keywords
Experimental Modeling of Eosinophil-Associated Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1095-4_21
Abstract: Eosinophils are an important subtype of leukocytes derived from bone marrow multipotent hematopoietic stem cells and represent about 1% of leukocytes in circulating blood. In homeostatic conditions, eosinophils reside in the intestine to maintain the… read more here.
Keywords: pancreatic cancer; eosinophil associated; associated diseases; chronic pancreatitis ... See more keywords
Stability of the Blood Eosinophilic Phenotype in Stable and Exacerbated COPD.
Sign Up to like & getrecommendations! Published in 2019 at "Chest"
DOI: 10.1016/j.chest.2019.04.012
Abstract: BACKGROUND There is controversy regarding the use of blood eosinophil levels as a biomarker of exacerbation risk and responsiveness of patients to inhaled corticosteroids (ICS). METHODS Patients in stable COPD with Gold Initiative for Chronic… read more here.
Keywords: blood eosinophil; discordance; eosinophil values; blood ... See more keywords
Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94835-9
Abstract: Blood eosinophil count is a useful measure in asthma or COPD management. Recent epidemiological studies revealed that body mass index (BMI) is positively associated with eosinophil counts. However, few studies focused on the role of… read more here.
Keywords: blood eosinophil; eosinophil counts; genetic background; study ... See more keywords
Expressions of Eotaxin-3, Interleukin-5, and Eosinophil-Derived Neurotoxin in Chronic Subdural Hematoma Fluids.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurotrauma"
DOI: 10.1089/neu.2018.5646
Abstract: Eosinophils induce inflammation by releasing cytokines and cytotoxic granule proteins. Infiltration of eosinophilic granulocytes occurs in the outer membrane of chronic subdural hematomas (CSDHs). Eosinophils play an important role in the growth of CSDHs. However,… read more here.
Keywords: chronic subdural; eosinophil derived; csdh fluids; eotaxin interleukin ... See more keywords
P123 Use of blood eosinophils to predict outcomes under inhaled maintenance treatment in steroid-naïve COPD patients in primary care: new user cohort study using the clinical practice research datalink
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.281
Abstract: Introduction and objectives Blood eosinophils are a potentially useful biomarker to guide inhaled corticosteroid (ICS) treatment in COPD. We aimed to investigate whether blood eosinophil count predicts the effect of maintenance treatment with ICS versus… read more here.
Keywords: primary care; maintenance; treatment; blood eosinophils ... See more keywords
Blood Eosinophil Endotypes across Asthma and Chronic Obstructive Pulmonary Disease (COPD)
Sign Up to like & getrecommendations! Published in 2022 at "Canadian Respiratory Journal"
DOI: 10.1155/2022/9656278
Abstract: Background Eosinophils were common inflammatory cells involved in the occurrence and development of various inflammatory diseases. Multiple recent studies have pointed to the increasingly important role of eosinophils in respiratory diseases. This article aims to… read more here.
Keywords: asthma chronic; blood eosinophil; copd; eosinophil ... See more keywords
Do Plasticizers within the Indoor Environment Increase Airway Allergen Responsiveness?
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202005-2048ed
Abstract: P, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360:1715–1721. 18. Horn BR, Robin ED, Theodore J, Van Kessel A. Total eosinophil counts in the management of bronchial asthma. N… read more here.
Keywords: chronic obstructive; respir; asthma; disease ... See more keywords
Peripheral blood eosinophil counts in COPD patients and its relationship with prescription of inhaled corticosteroid in real world setting in Japan
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa1117
Abstract: Background: Although recent retrospective studies suggest the possibility that peripheral blood (PB) eosinophil counts can predict the efficacy of inhaled corticosteroids (ICS) in COPD, the results are still inconsistent. In addition, the distribution of PB… read more here.
Keywords: real world; eosinophil counts; blood; prescription ... See more keywords
The reproducibility of COPD blood eosinophil counts
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.00427-2018
Abstract: Post hoc and pre-specified analyses of chronic obstructive pulmonary disease (COPD) randomised controlled trials have shown that higher blood eosinophil counts predict greater inhaled corticosteroid (ICS) effects on exacerbation prevention [1–5]. COPD patients with higher… read more here.
Keywords: reproducibility copd; eosinophil counts; blood eosinophil; eosinophil ... See more keywords
Blood eosinophil counts and the development of obstructive lung disease: the Kangbuk Samsung Health Study
Sign Up to like & getrecommendations! Published in 2021 at "European Respiratory Journal"
DOI: 10.1183/13993003.03823-2020
Abstract: Aim The impact of blood eosinophil counts on the development of chronic obstructive lung disease (COPD) is unknown. We investigated whether a higher blood eosinophil count was associated with the risk of developing obstructive lung… read more here.
Keywords: eosinophil counts; blood eosinophil; lung disease; eosinophil ... See more keywords