Eosinophil Activation Status in Separate Compartments and Association with Asthma
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2017.00075
Abstract: Asthma is frequently characterized by eosinophil-rich airway inflammation. Airway eosinophilia is associated with asthma exacerbations and likely plays a part in airway remodeling. Eosinophil recruitment from the bloodstream depends on circulating eosinophils becoming activated, which… read more here.
Keywords: surface proteins; eosinophil activation; circulating eosinophils; pre activated ... See more keywords
Proteomics of Eosinophil Activation
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2017.00159
Abstract: We recently identified and quantified >7,000 proteins in non-activated human peripheral blood eosinophils using liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) and described phosphoproteomic changes that accompany acute activation of eosinophils by interleukin-5 (IL5)… read more here.
Keywords: eosinophil activation; proteomics eosinophil; mass; activation ... See more keywords
CCL4 Regulates Eosinophil Activation in Eosinophilic Airway Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416149
Abstract: Eosinophilic chronic rhinosinusitis (ECRS) is a refractory airway disease accompanied by eosinophilic inflammation, the mechanisms of which are unknown. We recently found that CCL4/MIP-1β—a specific ligand for CCR5 receptors—was implicated in eosinophil recruitment into the… read more here.
Keywords: inflammation; ccl4; airway inflammation; eosinophil activation ... See more keywords