Essential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)
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DOI: 10.1021/acsinfecdis.1c00537
Abstract: The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evolution. A feasible effector for this process is eosinophil cationic protein (ECP, RNase 3), one of the main human eosinophil granule proteins,… read more here.
Keywords: rnase; activity; leishmanicidal mechanism; ecp h15a ... See more keywords
Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome
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DOI: 10.1038/s41598-017-04687-5
Abstract: Bullous Pemphigoid (BP) is an inflammatory rare autoimmune bullous dermatosis, which outcome cannot be predicted through clinical investigations. Eosinophils are the main immune infiltrated cells in BP. However, the release of Major Basic Protein (MBP),… read more here.
Keywords: protein; outcome; bullous pemphigoid; eosinophil cationic ... See more keywords
Cell Penetrating Peptide Derived from Human Eosinophil Cationic Protein Decreases Airway Allergic Inflammation
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DOI: 10.1038/s41598-017-12390-8
Abstract: Cell penetrating peptide derived from human eosinophil cationic protein (CPPecp) is a 10-amino-acid peptide containing a core heparan sulfate (HS)-binding motif of human eosinophil cationic protein (ECP). It binds and penetrates bronchial epithelial cells without… read more here.
Keywords: cationic protein; eosinophil cationic; human eosinophil;
Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein.
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DOI: 10.1093/trstmh/trx057
Abstract: Background This cohort study assessed urinary eosinophil cationic protein (ECP) as an indicator for urinary tract morbidity and inflammation indication related to single-dose or dual-dose praziquantel (PZQ) treatment. Methods Urinary ECP was measured at baseline,… read more here.
Keywords: ecp; treatment; urinary eosinophil; eosinophil cationic ... See more keywords
Clinical and immunological biomarkers in hypereosinophilic syndrome: the second step after diagnostic algorithms
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DOI: 10.3389/fmed.2025.1600728
Abstract: Background Idiopathic hypereosinophilic syndrome currently represents a major unmet need for all medical specialties dealing with this disease. Markers capable of characterising the wide variability of its clinical presentation are currently lacking. Objective This study… read more here.
Keywords: idiopathic hypereosinophilic; hypereosinophilic syndrome; eosinophil cationic; aureus enterotoxins ... See more keywords