Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Immunology"
DOI: 10.1002/eji.202250101
Abstract: Epithelial cytokines are involved in the orchestration of T1/T2 inflammatory patterns. We question the persistence of this trait in air–liquid interface (ALI) epithelial cultures and whether this local orientation can be related to systemic patterns… read more here.
Keywords: epithelial type; airway epithelial; blood eosinophil; alarmin ... See more keywords
Low and High Blood Eosinophil Counts as Biomarkers in Hospitalized Acute Exacerbations of COPD.
Sign Up to like & getrecommendations! Published in 2019 at "Chest"
DOI: 10.1016/j.chest.2019.02.406
Abstract: BACKGROUND Characterizing acute exacerbations of COPD (AECOPD) and individualizing therapy is challenging. Key exacerbation therapies include antibiotics and systemic corticosteroids. Blood eosinophils, when either low or high, may offer a simple, inexpensive distinction to predict… read more here.
Keywords: blood eosinophil; eosinophil counts; high blood; low high ... See more keywords
Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94835-9
Abstract: Blood eosinophil count is a useful measure in asthma or COPD management. Recent epidemiological studies revealed that body mass index (BMI) is positively associated with eosinophil counts. However, few studies focused on the role of… read more here.
Keywords: blood eosinophil; eosinophil counts; genetic background; study ... See more keywords
Biomarkers for differentiation of patients with asthma and chronic obstructive pulmonary disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asthma"
DOI: 10.1080/02770903.2017.1391281
Abstract: ABSTRACT Objective: Asthma and chronic obstructive pulmonary disease (COPD) are airflow limitation diseases with similar clinical manifestations but different pathophysiologic mechanisms. To implement the appropriate treatment, it is important to distinguish between asthma and COPD… read more here.
Keywords: blood eosinophil; eosinophil counts; feno levels; patients asthma ... See more keywords
Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD)
Sign Up to like & getrecommendations! Published in 2019 at "COPD: Journal of Chronic Obstructive Pulmonary Disease"
DOI: 10.1080/15412555.2019.1608172
Abstract: Abstract Although recently introduced in the pharmacological treatment algorithm of chronic obstructive pulmonary disease (COPD), there is a need for more data supporting the use of blood eosinophil counts as a biomarker to guide inhaled… read more here.
Keywords: blood eosinophil; risk; eosinophil counts; mortality ... See more keywords
Variability of blood eosinophils as a biomarker in asthma and COPD
Sign Up to like & getrecommendations! Published in 2018 at "Respirology"
DOI: 10.1111/resp.13200
Abstract: After a lifetime of being seen but not noticed, the blood eosinophil count has now taken centre stage as the most clinically accessible biomarker to aid in the management of asthma and COPD. Phenotyping has… read more here.
Keywords: blood eosinophil; eosinophil counts; blood eosinophils; blood ... See more keywords
Peripheral blood eosinophil counts in COPD patients and its relationship with prescription of inhaled corticosteroid in real world setting in Japan
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa1117
Abstract: Background: Although recent retrospective studies suggest the possibility that peripheral blood (PB) eosinophil counts can predict the efficacy of inhaled corticosteroids (ICS) in COPD, the results are still inconsistent. In addition, the distribution of PB… read more here.
Keywords: real world; eosinophil counts; blood; prescription ... See more keywords
The reproducibility of COPD blood eosinophil counts
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.00427-2018
Abstract: Post hoc and pre-specified analyses of chronic obstructive pulmonary disease (COPD) randomised controlled trials have shown that higher blood eosinophil counts predict greater inhaled corticosteroid (ICS) effects on exacerbation prevention [1–5]. COPD patients with higher… read more here.
Keywords: reproducibility copd; eosinophil counts; blood eosinophil; eosinophil ... See more keywords
Blood eosinophils in COPD and the future risk of pneumonia
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.00981-2018
Abstract: The eosinophil, whether in the blood or sputum, has been receiving increasing attention as a measure of treatment response or failure in patients with chronic obstructive pulmonary disease (COPD). A recent review by Bafadhel et… read more here.
Keywords: blood eosinophil; eosinophil counts; blood eosinophils; blood ... See more keywords
Blood eosinophil counts and the development of obstructive lung disease: the Kangbuk Samsung Health Study
Sign Up to like & getrecommendations! Published in 2021 at "European Respiratory Journal"
DOI: 10.1183/13993003.03823-2020
Abstract: Aim The impact of blood eosinophil counts on the development of chronic obstructive lung disease (COPD) is unknown. We investigated whether a higher blood eosinophil count was associated with the risk of developing obstructive lung… read more here.
Keywords: eosinophil counts; blood eosinophil; lung disease; eosinophil ... See more keywords
A Comprehensive Analysis of the Stability of Blood Eosinophil Levels
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the American Thoracic Society"
DOI: 10.1513/annalsats.202010-1249oc
Abstract: Rationale: Blood eosinophil counts are used to inform diagnosis/management of eosinophilic asthma. Objectives: Examine blood eosinophil variability and identify factors affecting eosinophil levels to inform clinical interpretation. Methods: Post hoc analysis to understand eosinophil variability… read more here.
Keywords: blood eosinophil; eosinophil levels; eosinophil counts; analysis ... See more keywords