Sirtuin 6 promotes eosinophil differentiation by activating GATA‐1 transcription factor
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DOI: 10.1111/acel.13418
Abstract: There is evidence emerging that exposure to cold temperatures enhances alternative activation of macrophages in white adipose tissue (WAT), which promotes adipocyte beiging and adaptive thermogenesis. Although we recently reported that NAD+‐dependent deacetylase sirtuin 6… read more here.
Keywords: sirtuin; myeloid sirt6; sirt6; eosinophil differentiation ... See more keywords
Human Bronchial Epithelial Cell‐derived Factors from Severe Asthmatic Subjects Stimulate Eosinophil Differentiation
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DOI: 10.1165/rcmb.2016-0262oc
Abstract: &NA; Activated bronchial epithelial cells (BEC) release various alarmins, including thymic stromal lymphopoietin (TSLP), that drive type 2 inflammation. We hypothesize that BEC‐derived factors promote in situ eosinophil differentiation and maturation, a process that is… read more here.
Keywords: bronchial epithelial; human bronchial; cell; derived factors ... See more keywords