Eosinophil and mast cell Siglecs: From biology to drug target
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DOI: 10.1002/jlb.2mr0120-352rr
Abstract: Mast cells and eosinophils are innate immune cells involved in both acute and chronic inflammatory responses. Siglecs are a family of cell surface receptors that share sialic acid binding activity. Over the past 20 years,… read more here.
Keywords: cell siglecs; biology; eosinophil mast; cell ... See more keywords
Role of Vasoactive Intestinal Peptide in Promoting the Pathogenesis of Eosinophilic Esophagitis (EoE)
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DOI: 10.1016/j.jcmgh.2017.09.006
Abstract: Eosinophilic esophagitis (EoE) is associated with eosinophil and mast cell accumulation, which promotes dysphagia and esophageal dysmotility. Cytokines and chemokines implicated in eosinophil-, mast cell–, and basophil-mediated EoE pathogenesis include interleukin (IL)-5, IL-13, thymic stromal… read more here.
Keywords: esophagitis eoe; eosinophil mast; pathogenesis; eosinophilic esophagitis ... See more keywords