Functional 2D Nanoplatforms Alleviate Eosinophilic Chronic Rhinosinusitis by Modulating Eosinophil Extracellular Trap Formation
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202307800
Abstract: The therapeutic outcomes of patients with eosinophilic chronic rhinosinusitis (ECRS) remain unsatisfactory, largely because the underlying mechanisms of eosinophilic inflammation are uncertain. Here, it is shown that the nasal secretions of ECRS patients have high… read more here.
Keywords: chronic rhinosinusitis; eosinophil extracellular; eosinophilic chronic; extracellular trap ... See more keywords
High Remission Rate in Eosinophilic Chronic Rhinosinusitis Following More Than Two Years of Dupilumab Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.70311
Abstract: This study aimed to evaluate the clinical remission rate and changes in medication use in patients with eosinophilic chronic rhinosinusitis (ECRS) treated with dupilumab for > 2 years. read more here.
Keywords: chronic rhinosinusitis; eosinophilic chronic; remission rate;
Differentiation of eosinophilic and non‐eosinophilic chronic rhinosinusitis on preoperative computed tomography using deep learning
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Otolaryngology"
DOI: 10.1111/coa.13988
Abstract: This study aimed to develop deep learning (DL) models for differentiating between eosinophilic chronic rhinosinusitis (ECRS) and non‐ECRS (NECRS) on preoperative CT. read more here.
Keywords: differentiation eosinophilic; eosinophilic chronic; chronic rhinosinusitis; deep learning ... See more keywords
Effect of Dupilumab on Depression in Asthma with Eosinophilic Chronic Rhinosinusitis in the Japanese Population.
Sign Up to like & getrecommendations! Published in 2021 at "International archives of allergy and immunology"
DOI: 10.1159/000519296
Abstract: INTRODUCTION Psychological disorders, such as depression, are markedly prevalent in patients with airway diseases. In this study, we assessed the effect of treatment with dupilumab, an IL-4 receptor α chain antibody, on depressive symptoms in… read more here.
Keywords: eosinophilic chronic; asthma eosinophilic; chronic rhinosinusitis; effect ... See more keywords
Profile of Tissue Immunoglobulin E in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000522624
Abstract: Introduction: Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) exhibits a poorer prognosis than noneCRSwNP. The aim of this study was to analyze the potential of total immunoglobulin E (tIgE) and specific IgE (sIgE) levels in… read more here.
Keywords: tige; nasal polyps; chronic rhinosinusitis; rhinosinusitis nasal ... See more keywords
The hMeDIP-Seq identified INPP4A as a novel biomarker for eosinophilic chronic rhinosinusitis with nasal polyps.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2022-0053
Abstract: Background: Eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP) is an endotype of chronic rhinosinusitis with nasal polyps characterized by more severe symptoms, a stronger association with asthma and a greater recurrence risk. It is unknown… read more here.
Keywords: nasal polyps; hydroxymethylation; chronic rhinosinusitis; rhinosinusitis nasal ... See more keywords
Enhanced Interferon-β Response Contributes to Eosinophilic Chronic Rhinosinusitis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02330
Abstract: Type I interferon (IFN-I, including IFN-α and IFN-β) response has been implicated in eosinophilic inflammation, in addition to antiviral function. This study aimed to investigate the role of IFN-I in the pathogenesis of eosinophilic chronic… read more here.
Keywords: eosinophilic chronic; response; ifn; chronic rhinosinusitis ... See more keywords