Eosinophilic COPD Patients Display a Distinctive Serum miRNA Profile From Asthma and Non-eosinophilic COPD.
Sign Up to like & getrecommendations! Published in 2019 at "Archivos de bronconeumologia"
DOI: 10.1016/j.arbres.2019.09.020
Abstract: BACKGROUND Asthma and chronic obstructive pulmonary disease (COPD) are common chronic airway diseases that may overlap in some individuals. Asthma COPD overlap (ACO) is a heterogeneous conditions that includes smoking-asthma (SA) and COPD with eosinophilia… read more here.
Keywords: copde; copde patients; eosinophilic copd; copd ... See more keywords
Late Breaking Abstract - Dose-ranging study of mepolizumab in eosinophilic COPD
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa1366
Abstract: Background: Patients with eosinophilic COPD & frequent exacerbations may benefit from mepolizumab (MEP) treatment. Objective: Assess efficacy & safety of 2 MEP doses vs placebo (PBO) in COPD with blood eosinophils ≥150 cells/µL [screening] or… read more here.
Keywords: mep; pbo; eosinophilic copd; rate ... See more keywords
ACO: Time to move from the description of different phenotypes to the treatable traits
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0210915
Abstract: BACKGROUND Asthma-COPD overlap (ACO) is a term that encompasses patients with characteristics of two conditions, smoking asthmatics or COPD patients with asthma-like features such as high bronchodilator response or blood eosinophil count ≥300 cells/μL. The… read more here.
Keywords: copd patients; eosinophilic copd; smoking asthmatics; different phenotypes ... See more keywords
Prevalence and Baseline Clinical Characteristics of Eosinophilic Chronic Obstructive Pulmonary Disease: A Meta-Analysis and Systematic Review
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2019.00282
Abstract: Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with different clinical and pathophysiological characteristics. Cumulative evidence shows that eosinophil levels may be connected to the therapeutic effects and phenotype of COPD. However, the… read more here.
Keywords: analysis; prevalence; disease; eosinophilic copd ... See more keywords
Eosinophilic COPD - a distinct phenotype of the disease.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in respiratory medicine"
DOI: 10.5603/arm.a2017.0045
Abstract: Chronic Obstructive Pulmonary Disease (COPD) has been traditionally associated with neutrophilic inflammation of the bronchi. Studies from the early 1990s demonstrated that eosinophils may also get into the lower airways of patients with COPD and… read more here.
Keywords: phenotype; disease eosinophilic; disease; eosinophilic copd ... See more keywords