Abstract P2-05-23: EP3-receptor expression is a prognostic marker for overall survival and progression-free survival in sporadic breast cancer
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DOI: 10.1158/1538-7445.sabcs16-p2-05-23
Abstract: Aim: Prostaglandins are tissue hormones with a variety of biological effects and are mainly associated with infection and inflammation. However, elevated prostaglandin synthesis, especially of prostaglandin E2 (PGE2) caused by overexpression of cyclooxygenase-2 (COX-2), has… read more here.
Keywords: receptor; ep3 receptor; expression; breast cancer ... See more keywords
Discovery and Functional Validation of EP3 Receptor Ligands with Therapeutic Potential in Cardiovascular Disease
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DOI: 10.3390/ijms26104879
Abstract: The prostaglandin E2 receptor EP3 is emerging as a promising therapeutic target in cardiovascular diseases because of its involvement in vascular inflammation, platelet aggregation, and vasoconstriction. However, selective EP3 ligands with validated biological activities are… read more here.
Keywords: receptor; ep3 receptor; ligands therapeutic; ep3 ... See more keywords