Tailored PGE2 Immunomodulation of moDCs by Nano-Encapsulated EP2/EP4 Antagonists
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DOI: 10.3390/ijms24021392
Abstract: Prostaglandin E2 (PGE2) is an important maturation mediator for dendritic cells (DCs). However, increased PGE2 levels in the tumor exert immunosuppressive effects on DCs by signaling through two E-Prostanoid (EP) receptors: EP2 and EP4. Blocking… read more here.
Keywords: modcs; ep4 antagonists; ep2 ep4; tailored pge2 ... See more keywords