Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP4 receptors and their mediation of cyclooxygenase‐2 induction in HCA‐7 human colon cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.04.014
Abstract: ABSTRACT Microbiota produce short chain fatty acids (SCFAs), which are known to maintain gut homeostasis, by the fermentation of dietary fiber in the human colon. Among SCFAs, butyrate has been considered as the most physiologically… read more here.
Keywords: ep4 receptors; butyrate uptake; human colon; cancer ... See more keywords
Complementary roles of EP2 and EP4 receptors in malignant glioma.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of pharmacology"
DOI: 10.1111/bph.16148
Abstract: BACKGROUND AND PURPOSE Glioblastoma (GBM) is the most aggressive brain tumor in the central nervous system, but the current treatment is very limited and overall unsatisfactory. PGE2 -initiated cAMP signaling via EP2 and EP4 receptors… read more here.
Keywords: growth; ep2 ep4; roles ep2; gbm ... See more keywords