Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics
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DOI: 10.1007/s10822-020-00332-y
Abstract: The exchange proteins activated by cAMP (EPAC) are implicated in a large variety of physiological processes and they are considered as promising targets for a wide range of therapeutic applications. Several recent reports provided evidence… read more here.
Keywords: allosteric inhibitor; modeling epac1; molecular dynamics; interactions allosteric ... See more keywords