Cell-specific expression of Epac2 in the subventricular and subgranular zones
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DOI: 10.1186/s13041-019-0537-1
Abstract: AimcAMP signal transduction cascade activation is important in regulating neurogenesis in adult rodents by increasing the proliferation of newborn cells. Although the ventricular-subventricular zone (V-SVZ) and subgranular zone (SGZ) both contain large populations of neural… read more here.
Keywords: epac2; specific expression; svz sgz; expression epac2 ... See more keywords
Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release
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DOI: 10.7554/elife.80747
Abstract: Repeated exposure to drugs of abuse results in an upregulation of cAMP signaling in the mesolimbic dopamine system, a molecular adaptation thought to be critically involved in the development of drug dependence. Exchange protein directly… read more here.
Keywords: epac2; dopamine release; dopamine; dopamine neurons ... See more keywords