EPAS1/HIF2α correlates with features of low-risk neuroblastoma and with adrenal chromaffin cell differentiation during sympathoadrenal development.
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DOI: 10.1016/j.bbrc.2018.12.076
Abstract: The hypoxia inducible transcription factor EPAS1/HIF2α has been described as an oncogene and a potential therapeutic target in neuroblastoma. Our analysis of several neuroblastoma tumour expression datasets does not support an oncogenic role, instead EPAS1… read more here.
Keywords: low risk; adrenal chromaffin; cell; epas1 hif2 ... See more keywords