Oxygen regulates proliferation and phenotype in the RS0 SDH-deficient pheochromocytoma cell line.
Sign Up to like & getrecommendations! Published in 2025 at "Endocrine-related cancer"
DOI: 10.1530/erc-25-0022
Abstract: The RS0 cell line is a rat-derived pheochromocytoma line developed as a model to study pheochromocytoma/paraganglioma caused by hereditary mutations of the SDHB gene. Previous studies demonstrated that xenografts of the RS0 parent tumor replicate… read more here.
Keywords: cell line; cell; proliferation; line ... See more keywords
Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2022.281698
Abstract: Gain-of-function mutations in the EPAS1/HIF2A gene have been identified in patients with hereditary erythrocytosis that can be associated with the development of paraganglioma, pheochromocytoma and somatostatinoma. In the present study, we describe a unique European… read more here.
Keywords: patients erythrocytosis; genetic variants; erythrocytosis; identified patients ... See more keywords