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   Articles with "epcs" as a keyword



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OGR1 mediates the inhibitory effects of acidic environment on proliferation and angiogenesis of endothelial progenitor cells

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recommendations! Published in 2019 at "Cell Biology International"

DOI: 10.1002/cbin.11179

Abstract: Ovarian cancer G‐protein‐coupled receptor 1 (OGR1), an acid‐sensitive receptor, plays a key proton‐sensing role through stimulation of inositol phosphate formation. Avascular necrosis of the femoral head is characterized by apoptosis of bone cells mainly resulting… read more here.

Keywords: angiogenesis; ogr1; acidic environment; proliferation ... See more keywords
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SDF-1 secreted by mesenchymal stem cells promotes the migration of endothelial progenitor cells via CXCR4/PI3K/AKT pathway.

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recommendations! Published in 2021 at "Journal of molecular histology"

DOI: 10.1007/s10735-021-10008-y

Abstract: Cell-based therapeutics bring great hope in areas of unmet medical needs. Mesenchymal stem cells (MSCs) have been suggested to facilitate neovascularization mainly by paracrine action. Endothelial progenitor cells (EPCs) can migrate to ischemic sites and… read more here.

Keywords: via cxcr4; migration; epcs; stem cells ... See more keywords
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Fluid Shear Stress Ameliorates Prehypertension-Associated Decline in Endothelium-Reparative Potential of Early Endothelial Progenitor Cells

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recommendations! Published in 2022 at "Journal of Cardiovascular Translational Research"

DOI: 10.1007/s12265-022-10235-y

Abstract: This study investigated the effects of prehypertension and shear stress on the reendothelialization potential of human early EPCs and explored its potential mechanisms. Early EPCs from the prehypertensive patients showed reduced migration and adhesion in… read more here.

Keywords: early epcs; epcs; shear stress; potential early ... See more keywords

BMP‐2 induces angiogenesis by provoking integrin &agr;6 expression in human endothelial progenitor cells

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recommendations! Published in 2018 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2018.02.021

Abstract: Graphical abstract Figure. No Caption available. Abstract Bone morphogenetic protein‐2 (BMP‐2) is a multifunctional cytokine, capable of governing several cellular functions, including proliferation, motility, differentiation, and angiogenesis. Circulating endothelial progenitor cells (EPCs) have been shown… read more here.

Keywords: bmp; angiogenesis; integrin agr; endothelial progenitor ... See more keywords
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A preventive injection of endothelial progenitor cells prolongs lifespan in stroke-prone spontaneously hypertensive rats.

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recommendations! Published in 2018 at "Clinical science"

DOI: 10.1042/cs20180360

Abstract: There is a pressing need for new approaches to prevent stroke. Endothelial progenitor cells (EPCs) promote vascular repair and revascularization in the ischemic brain. The present study sought to evaluate whether preventive delivery of EPCs… read more here.

Keywords: progenitor cells; stroke prone; preventive injection; endothelial progenitor ... See more keywords
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MiR-17-5p promotes the endothelialization of endothelial progenitor cells to facilitate the vascular repair of aneurysm by regulating PTEN-mediated PI3K/AKT/VEGFA pathway

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recommendations! Published in 2020 at "Cell Cycle"

DOI: 10.1080/15384101.2020.1857958

Abstract: ABSTRACT The endothelialization of endothelial progenitor cells (EPCs) was proven to facilitate the vascular repair of aneurysm. MiR-17-5p regulated angiogenesis in various cancers. This research focused on exploring the effect of miR-17-5p on EPCs and… read more here.

Keywords: mir; repair aneurysm; pi3k akt; epcs ... See more keywords
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Bone mesenchymal stem cells-derived miR-223-3p-containing exosomes ameliorate lipopolysaccharide-induced acute uterine injury via interacting with endothelial progenitor cells.

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recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.2001185

Abstract: Bone mesenchymal stem cells (BMSCs) have been used for the treatment of acute uterine injury (AUI)-induced intrauterine adhesion (IUA) via interacting with the endothelial progenitor cells (EPCs), and BMSCs-derived exosomes (BMSCs-exo) may be the key… read more here.

Keywords: bone mesenchymal; bmscs exo; epcs; mir 223 ... See more keywords
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AB0220 ALPHA- SMOOTH MUSCLE ACTIN EXPRESSION ON ENDOTHELIAL PROGENITORS CELLS OF SYSTEMIC SCLEROSIS PATIENTS: POSSIBLE ROLE IN THE ENDOTHELIAL-TO-MESENCHIMAL TRANSITION PROCESS

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recommendations! Published in 2019 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2019-eular.6342

Abstract: Background Endothelial-to-mesenchymal transition (EndoMT), a newly recognized type of cellular transdifferentiation, seems to be involved in Systemic Sclerosis (SSc) pathogenesis. In this process endothelial cells lose their specific markers, and acquire a mesenchymal phenotype, thus… read more here.

Keywords: none declared; sma; epcs; early epcs ... See more keywords

Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3&bgr;/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia

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recommendations! Published in 2017 at "Circulation Research"

DOI: 10.1161/circresaha.117.310619

Abstract: Rationale: Endothelial progenitor cells (EPCs) respond to stromal cell–derived factor 1 (SDF-1) through chemokine receptors CXCR7 and CXCR4. Whether SDF-1 receptors involves in diabetes mellitus–induced EPCs dysfunction remains unknown. Objective: To determine the role of… read more here.

Keywords: kinase; epcs transduced; lentivirus; epcs ... See more keywords
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Development of Bio-Artificial Micro-Vessels with Immunosuppressive Capacities: A Hope for Future Transplantations and Organoids

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-121395

Abstract: Background: From creating artificial organs to transplantation and cancer, newly formed vessels are playing a critical role. Endothelial progenitor cells (EPCs) are non-differentiated endothelial cells which are present in circulation and are applied in neovascularization… read more here.

Keywords: vessel; micro; epcs; blood ... See more keywords
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Senescence Induces Dysfunctions in Endothelial Progenitor Cells and Osteoblasts by Interfering Translational Machinery and Bioenergetic Homeostasis

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recommendations! Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19071997

Abstract: Age-related bone diseases are partly caused by impaired bone integrity, which are closely related to osteoblasts’ activity and angiogenesis. Endothelial progenitor cells (EPCs) are the initiators of angiogenesis and found to have senescent-induced dysfunctions. The… read more here.

Keywords: progenitor cells; senescence; senescent epcs; endothelial progenitor ... See more keywords