LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ependymomas" as a keyword



Photo from archive.org

Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome

Sign Up to like & get
recommendations! Published in 2020 at "Child's Nervous System"

DOI: 10.1007/s00381-020-04655-x

Abstract: Introduction Young age is an adverse prognostic factor in children with ependymomas. Treatment of these infants is challenging since beneficial therapeutic options are limited. As ependymomas are considered a biologically heterogeneous group, we aimed to… read more here.

Keywords: underlying genetic; posterior fossa; ependymomas; infancy underlying ... See more keywords

Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas

Sign Up to like & get
recommendations! Published in 2024 at "Acta Neuropathologica"

DOI: 10.1007/s00401-023-02674-x

Abstract: The diagnosis of ependymoma has moved from a purely histopathological review with limited prognostic value to an integrated diagnosis, relying heavily on molecular information. However, as the integrated approach is still novel and some molecular… read more here.

Keywords: methylation; survival; epn; prediction ... See more keywords

Radiotherapy in addition to surgical resection may not improve overall survival in WHO grade II spinal ependymomas

Sign Up to like & get
recommendations! Published in 2020 at "Clinical Neurology and Neurosurgery"

DOI: 10.1016/j.clineuro.2019.105632

Abstract: OBJECTIVES Spinal ependymomas are rare intramedullary neoplasms. The paucity of cases limits the ability to conduct large prospective studies. Current guidelines recommend maximal safe resection followed by adjuvant radiotherapy (RT) in cases of grade II… read more here.

Keywords: grade spinal; radiotherapy; survival; ependymomas ... See more keywords

EPEN-17.IN VITRO MODELLING OF PEDIATRIC SUPRATENTORIAL EPENDYMOMAS USING CEREBRAL ORGANOIDS

Sign Up to like & get
recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae064.219

Abstract: Abstract BACKGROUND Ependymomas (EPN) are glial tumors of the central nervous system occurring in children and adults. ZFTA-fusion positive and YAP1-fusion positive EPN are the main supratentorial (ST) subgroups in children. While most ST-EPN-YAP1 patients… read more here.

Keywords: fusion; yap1; zfta; tumor ... See more keywords

TMET-36. INCREASED METHIONINE CYCLE DRIVES PYRIMIDINE METABOLISM IN LETHAL PEDIATRIC EPENDYMOMAS

Sign Up to like & get
recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae165.1174

Abstract: Supratentorial ependymomas (ST-EPN) are pediatric brain tumors found in the cerebral hemisphere, driven by the oncogenic fusion of ZFTA with RELA. Other than surgery and radiotherapy, these tumors do not have effective therapeutic options. Recurrent… read more here.

Keywords: tmet increased; pyrimidine metabolism; methionine cycle; metabolism ... See more keywords
Photo by satheeshsankaran from unsplash

Intracranial ependymomas: molecular insights and translation to treatment

Sign Up to like & get
recommendations! Published in 2019 at "Brain Pathology"

DOI: 10.1111/bpa.12781

Abstract: Ependymomas are primary central nervous system tumors (CNS), arising within the posterior fossa and supratentorial regions of the brain, and in the spine. Over the last decade, research has resulted in substantial insights into the… read more here.

Keywords: treatment; molecular insights; ependymomas; ependymomas molecular ... See more keywords

Microsurgery resection of giant cervicothoracic spinal ependymoma: Two-dimensional operative video

Sign Up to like & get
recommendations! Published in 2024 at "Surgical Neurology International"

DOI: 10.25259/sni_317_2024

Abstract: Background: Ependymomas, rare glial brain tumors, account for read more here.

Keywords: spinal ependymoma; resection giant; ependymomas; resection ... See more keywords

MRI Features of Intracranial Anaplastic Ependymomas: A Comparison of Supratentorial and Infratentorial Lesions

Sign Up to like & get
recommendations! Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.01063

Abstract: Background: Several previous reports of anaplastic ependymomas have described their imaging features, and most of these studies were case reports. However, no studies have compared the magnetic resonance imaging (MRI) features between the infratentorial and… read more here.

Keywords: mri features; anaplastic ependymomas; intracranial anaplastic; ependymomas ... See more keywords