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Extracellular Prostaglandins E1 and E2 and Inflammatory Cytokines Are Regulated by the Senescence Program in Potentially Premalignant Oral Keratinocytes

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14112636

Abstract: Potentially pre-malignant lesions (PPOLs) are composed of keratinocytes that are either mortal (MPPOL) or immortal (IPPOL) in vitro. We report here that MPPOL, but not generally IPPOL keratinocytes upregulate various extracellular tumor promoting cytokines (interleukins… read more here.

Keywords: senescence program; premalignant oral; senescence; oral keratinocytes ... See more keywords