Functional non-coding polymorphism in an EPHA2 promoter PAX2 binding site modifies expression and alters the MAPK and AKT pathways
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DOI: 10.1038/s41598-017-10117-3
Abstract: To identify possible genetic variants influencing expression of EPHA2 (Ephrin-receptor Type-A2), a tyrosine kinase receptor that has been shown to be important for lens development and to contribute to both congenital and age related cataract… read more here.
Keywords: pax2 binding; binding site; mapk akt; epha2 promoter ... See more keywords