Presenilin Regulates Retinotectal Synapse Formation through EphB2 Receptor Processing
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22638
Abstract: As the catalytic component of γ‐secretase, presenilin (PS) has long been studied in the context of Alzheimer’s disease through cleaving the amyloid precursor protein. PS/γ‐secretase, however, also cleaves a multitude of single‐pass transmembrane proteins that… read more here.
Keywords: receptor; presenilin; ephb2 receptor; synapse formation ... See more keywords
Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Cell International"
DOI: 10.1186/s12935-017-0409-7
Abstract: BackgroundMedulloblastoma is one of the most common types of pediatric brain tumor characterized by the subpopulation of cells that exhibit high invasive potential and radioresistant properties. In addition, dysregulated function and signaling by Eph family… read more here.
Keywords: viability; invasion; medulloblastoma; ephb2 receptor ... See more keywords