Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly
Sign Up to like & getrecommendations! Published in 2018 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddy218
Abstract: Central conducting lymphatic anomaly (CCLA) is one of the complex lymphatic anomalies characterized by dilated lymphatic channels, lymphatic channel dysmotility and distal obstruction affecting lymphatic drainage. We performed whole exome sequencing (WES) of DNA from… read more here.
Keywords: ephb4; central conducting; lymphatic anomaly; conducting lymphatic ... See more keywords
Endothelial EphB4 maintains vascular integrity and transport function in adult heart
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DOI: 10.7554/elife.45863
Abstract: The homeostasis of heart and other organs relies on the appropriate provision of nutrients and functional specialization of the local vasculature. Here, we have used mouse genetics, imaging and cell biology approaches to investigate how… read more here.
Keywords: endothelial ephb4; ephb4 maintains; adult heart; heart ... See more keywords