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Ligand-Dependent and Ligand-Independent Effects of Ephrin-B2–EphB4 Signaling in Melanoma Metastatic Spine Disease

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22158028

Abstract: Tumor–endothelial cell interactions represent an essential mechanism in spinal metastasis. Ephrin-B2–EphB4 communication induces tumor cell repulsion from the endothelium in metastatic melanoma, reducing spinal bone metastasis formation. To shed further light on the Ephrin-B2–EphB4 signaling… read more here.

Keywords: melanoma; endothelial ephrin; ephrin; metastasis ... See more keywords